Down sendromlu akut lenfoblastik lösemi olgusunda kemoterapi sonrasi fungal infeksiyona sekonder gelişen spontan pnömotoraks
Küçük Resim Yok
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Spontan pnömotoraks primer olabileceği gibi, kronik obstrüktif akciğer hastalığı, ağır astım krizi, infeksiyonlar, histiyositozis ve malign hastalıklara sekonder olarak da gelişebilmektedir. İnfeksiyonlar arasında tüberküloz, pneumocystis carinii pnömonisi, nekrotizan pnömoniler ve fungal infeksiyonlar ön sıralarda gelmektedir. Bu yazıda, akut lenfoblastik lösemi tedavisi esnasında, fungal infeksiyona sekonder spontan pnömotoraks gelişen bir olgu sunulmaktadı r. Hasta 18 yaşında, akut lenfoblastik lösemi tanısı ile hastaneye yatırılmış Down sendromlu bir olgudur. Nötropenik dönemde çekilen akciğer grafisinde bilateral fungal infiltrasyonu düşündüren görünüm ve sağda hidropnömotoraks ile uyumlu görünüm saptanmıştır. Olguya, kapalı su altı drenajı uygulanmış ve antifungal antibiyotik dozu artırılmıştır. Bu tedaviden fayda gören olgu iki hafta içinde düzelmiş ve drenaja son verilmiştir. Lösemi tedavisi de tamamlanan olgu halen izlenmektedir.
Spontaneous pneumothorax may occur primarily or secondary due to chronic obstructive pulmonary disease, severe asthma crisis, infections, histiocytosis or malignant conditions. Tuberculosis, pneumocystis carinii infection, necrotizing pneumonias and fungal infections are well-documented causes of spontaneous pneumothorax. We here present a case with spontaneous pneumothorax due to fungal infection in the treatment period of acute lymphoblastic leukemia. The patient was diagnosed as acute lymphoblastic leukemia accompanying Down syndrome. The chest Xray in the neutropenic period revealed probable bilateral fungal infiltration and hydropneumothorax at the right side. The patient was treated with closed chest tube drainage and appropriate antibiotherapy. Therapy was resulted with cure in two weeks and drainage was ended. After completing the treatment for leukemia, the patient has been under follow-up with remission in the aspect of leukemia and hydropneumothorax.
Spontaneous pneumothorax may occur primarily or secondary due to chronic obstructive pulmonary disease, severe asthma crisis, infections, histiocytosis or malignant conditions. Tuberculosis, pneumocystis carinii infection, necrotizing pneumonias and fungal infections are well-documented causes of spontaneous pneumothorax. We here present a case with spontaneous pneumothorax due to fungal infection in the treatment period of acute lymphoblastic leukemia. The patient was diagnosed as acute lymphoblastic leukemia accompanying Down syndrome. The chest Xray in the neutropenic period revealed probable bilateral fungal infiltration and hydropneumothorax at the right side. The patient was treated with closed chest tube drainage and appropriate antibiotherapy. Therapy was resulted with cure in two weeks and drainage was ended. After completing the treatment for leukemia, the patient has been under follow-up with remission in the aspect of leukemia and hydropneumothorax.
Açıklama
Anahtar Kelimeler
Kulak, Burun, Boğaz
Kaynak
Türk Toraks Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
2
