Yeasts in apical periodontitis
Küçük Resim Yok
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Int Amer Assoc Dental Researchi A D R/A A D R
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Microbiological reports of apical periodontitis have revealed that yeasts can be isolated from approximately 5-20% of infected root canals. They occur either in pure cultures or together with bacteria. Almost all isolated yeasts belong to the genus Candida, and the predominant species is C. albicans. Pheno- and genotypic profiles of C. albicans isolates show heterogeneity comparable with those of isolates from other oral sites. C. albicans expresses several virulence factors that are capable of infecting the dentin-pulp complex, including dentinal tubules. This causes, consequentially, an inflammatory response around the root apex, which suggests a pathogenic role for this organism in apical periodontitis. Yeasts are particularly associated with persistent root canal infections that do not respond favorably to conservative root canal therapy. This may be due to the resistance of all oral Candida species against a commonly used topical medicament, calcium hydroxide. However, other antimicrobial agents may offer alternative therapeutic approaches and improve the treatment of these persistent cases of apical periodontitis.
Açıklama
Anahtar Kelimeler
apical periodontitis, Candida, endodontics, yeast infection
Kaynak
Critical Reviews in Oral Biology & Medicine
WoS Q Değeri
Q1
Scopus Q Değeri
N/A
Cilt
14
Sayı
2
