Recommendations for Research to Develop a Patient-Centered Clinical Follow-Up Protocol for Oral Epithelial Dysplasia

Küçük Resim Yok

Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wiley

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Oral epithelial dysplasia (OED) is the primary histological marker for assessing the progression of oral potentially malignant disorders (OPMDs) to cancer. Despite challenges in grading and low inter-pathologist reproducibility, OED severity remains the key predictor of malignant transformation. However, globally accepted guidelines for OED monitoring are lacking, despite calls for individualized management based on host and lesion characteristics. The proposed research protocol involves acquiring high-quality intraoral images, assessing oral hygiene and periodontal status, eliminating chronic mechanical irritation and Candida infections, and applying adjunctive diagnostic methods like toluidine blue staining, optical evaluation, and brush cytology. Tailored follow-up regimens based on individual risk assessments are emphasized, with frequent monitoring for high-grade dysplasia or patients at higher risk of progression. Therefore, effective OED management should consider the patient's immune status, dietary habits, and oral microbiota, aiming to develop personalized treatment strategies that optimize patient-centered care.

Açıklama

Anahtar Kelimeler

comprehensive health care, follow-up monitoring, oral cancer, oral epithelial dysplasia

Kaynak

Head and Neck-journal for The Sciences and Specialties of The Head and Neck

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

47

Sayı

1

Künye

Güneri, P., Bolukbasi, G., Ilhan, B., Epstein, J. B., & Warnakulasuriya, S. (2025). Recommendations for research to develop a Patient‐Centered clinical Follow‐Up protocol for oral epithelial dysplasia. Head & Neck, 47(1), 7-13.