Inhibitory effects of chickpea and Tribulus terrestris on lipase, ?-amylase and ?-glucosidase
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The total saponin content and its in vitro bioaccessibilities in Tribulus terrestris and chickpea were determined by a static in vitro digestion method (COST FA1005 Action INFOGEST). Also, in vitro inhibitory effects of the chosen food samples on lipid and starch digestive enzymes were determined by evaluating the lipase, ?-amylase and ?-glucosidase activities. The tested T. terrestris and chickpea showed inhibitory activity against ?-glucosidase (IC50 6967 ± 343 and 2885 ± 85.4 µg/ml, respectively) and ?-amylase (IC50 343 ± 26.2 and 167 ± 6.12 µg/ml, respectively). The inhibitory activities of T. terrestris and chickpea against lipase were 15.3 ± 2.03 and 9.74 ± 1.09 µg/ml, respectively. The present study provides the first evidence that these food samples (T. terrestris, chickpea) are potent inhibitors of key enzymes in digestion of carbohydrates and lipids in vitro. © 2016 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Chickpea, In vitro bioaccessibility, Inhibitors, Lipase, Saponins, Tribulus terrestris, ?-Amylase, ?-Glucosidase
Kaynak
Food Chemistry
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
205
