Single-fiber EMG in Meniere's Disease
Küçük Resim Yok
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kesin etyolojisi bilinmeyen ve bir kanallopati hipotezi önerilmiş olan Meniere hastalarında motor son plak fonksiyon ( MSP) işlevini değerlendirmek. Yöntem: Meniere hastalığı tanısı almış 20 (13 kadın, 7 erkek) ve sağlıklı normal kontrol 12 (4 kadın 8 erkek) olgu, Extensor Digitorum Communis kasına istemli kasılma sırasında tek lif-EMG , üst ve alt ekstremite sinir iletim çalışmaları ve Extensor Digitorum Communis kasına konsantrik iğne EMG ile değerlendirildi. Her bir MD olgusu için ortalama jitter değerleri ölçüldü ve bu değerler normal kontrollerden elde edilen değerler ile karşılaştırıldı. Bulgular: Meniere hastalarının ortalama jitter değerleri normal kontrol olgularının değerlerinden farklı bulunmadı. Sonuç: Bulgularımız nöromuskuler ileti defekti ile uyumlu olmasa bile MD patogenezinde kanal disfonksiyonu varlığını dışlamaz.
Objective: To assess neuromuscular transmission (NMT) in patients with Meniere's disease (MD), in which the precise etiology is unknown and a channelopathy hypothesis has been proposed Methods: Single fiber electromyography (SFEMG) during voluntary contraction of the extansor digitorum communis muscle, nerve conduction studies of upper and lower extremities and concentric needle electromyography of the extensor digitorum communis were performed on 20 patients (13 female, 7 male) with MD and 12 age-matched normal controls (4 female, 8 male). Mean jitter value was calculated for each subject and was compared with the values recorded from normal controls. Results: The mean jitter values of the MD group were not different from the mean jitter values of normal control subjects. Conclusion: Even though our findings are not consistent with neuromuscular conduction defect, this doesn’t exclude presence of channelopathy in the pathogenesis of MD.
Objective: To assess neuromuscular transmission (NMT) in patients with Meniere's disease (MD), in which the precise etiology is unknown and a channelopathy hypothesis has been proposed Methods: Single fiber electromyography (SFEMG) during voluntary contraction of the extansor digitorum communis muscle, nerve conduction studies of upper and lower extremities and concentric needle electromyography of the extensor digitorum communis were performed on 20 patients (13 female, 7 male) with MD and 12 age-matched normal controls (4 female, 8 male). Mean jitter value was calculated for each subject and was compared with the values recorded from normal controls. Results: The mean jitter values of the MD group were not different from the mean jitter values of normal control subjects. Conclusion: Even though our findings are not consistent with neuromuscular conduction defect, this doesn’t exclude presence of channelopathy in the pathogenesis of MD.
Açıklama
Anahtar Kelimeler
Nörolojik Bilimler
Kaynak
Journal of Neurological Sciences (Turkish)
WoS Q Değeri
Scopus Q Değeri
Cilt
29
Sayı
1
