The effects of inhalational anaesthesia (Isoflurane) and total intra'venous anaesthesia (Propofol) on postoperative renal function and perioperative hemodynamics during renal transplantation [Renal tranplantasyonda inhalasyon anestezisi (Isofluran) ve TIVA'nin (Propofol) peroperatif hemodinami ve postoreratif bobrek fonksiyonlari uzerine etkileri]
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The effects inhalational anesthesia with isoflurane and total intravenous anesthesia with propofol on postoperative renal function and perioperative hemodynamics were compared in 20 patients undergoing renal transplantation. In the isoflurane group, anesthesia was induced by 2 µ/kg fentanyl, 5 mg/kg thiopentone, 0.5 mg/kg atracurium and maintained by % 0.5- 1.5 isoflurane. In the propofol group, anesthesia was induced by 2 µg/kg fentanyl, 2 mg/kg propofol ve 0.5 mg/kg atracurium and maintained by 3-12 mg/kg/h propofol. Heart rate, arterial blood pressure, pulmonary capillary wedge pressure and central venous pressure were checked at 10 min. interval during the perioperative period. Serum urea, creatinine, Na+, K+, daily urine output, creatinine clearance, urine urea and creatinine and on the 1st, 2nd, 3th postoperative days. We concluded that TIVA with propofol could be an alternative to inhalational anesthesia with isoflurane during renal transplantation, because the former has perioperaive hemadynamic stability and doesn't have negative effects on renal function postoperatively.