Gender-Related Differences in Patients with Acute Heart Failure: Observation from the Journey Heart Failure—Turkish Population Study
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Society of Cardiology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Gender-related clinical variations in patients with acute heart failure have been described in previous studies. However, there is still a lack of research on gender differences in patients hospitalized for acute heart failure in Türkiye. The aim of this study is to compare the clinical features, in-hospital approaches, and outcomes of male and female patients hospitalized for acute heart failure. Methods: Differences in clinical characteristics, medication prescription, hospital management, and outcomes between males and females with acute heart failure were investigated from the Journey Heart Failure—Turkish Population study. Results: Nine hundred eighteen patients (57.2%) were men and 688 (42.8%) were women. Women were older than men (70.48 ± 13.20 years vs. 65.87 ± 12.82 years; P < .001). The frequency of comorbidities such as hypertension (72.7% vs. 62.4%, P <.001), diabetes (46.5% vs. 38.5%, P= .001), atrial fibrillation (46.5% vs. 33.4%, P < .001), New York Heart Association class III-IV symptoms (80.6% vs. 71.2%, P= .001), and dyspnea in the rest (73.8% vs. 68.3%, P= .044) were more common in women on admission. Male patients were more frequently hospitalized with reduced left ventricular ejection fraction (51.0% vs. 72.4%, P < .001). In-hospital mortality was higher among female patients (9.3% vs. 6.4%, P = .022). Higher New York Heart Association class, lower estimated glomerular filtration rate, higher N-terminal pro-B type natriuretic peptide on admission, and mechanical ventilation usage were the independent parameters of in-hospital mortality, whereas the female gender was not. Conclusion: Our study clearly demonstrated the diversity in presentation, management, and in-hospital outcomes of acute heart failure between male and female patients. Although left ventricular systolic functions were better in female patients, in-hospital mortality was higher. Recognizing these differences in the management of heart failure in different sexes will serve better results in clinical practice. Copyright@Author(s) -
Açıklama
Anahtar Kelimeler
acute heart failure, gender differences, Heart failure, acetylsalicylic acid, creatinine, acute heart failure, aged, Article, artificial ventilation, controlled study, coronary angiography, diabetes mellitus, diastolic blood pressure, estimated glomerular filtration rate, female, glucose blood level, hospital mortality, human, hypertension, in-hospital mortality, international normalized ratio, length of stay, major clinical study, male, New York Heart Association class, observational study, outcome assessment, oxygen saturation, percutaneous coronary intervention, prospective study, QRS interval, sex difference, systolic blood pressure, Turk (people), urea nitrogen blood level, atrial fibrillation, heart failure, heart left ventricle function, heart stroke volume, patient, sex factor, Atrial Fibrillation, Female, Heart Failure, Humans, Male, Patients, Sex Factors, Stroke Volume, Ventricular Function, Left
Kaynak
Anatolian Journal of Cardiology
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
27
Sayı
11
