Adsorptive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode
Küçük Resim Yok
Tarih
1997
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A highly sensitive adsorptive stripping procedure for trace measurement of the anticancer drug tamoxifen is described. The method is based on controlled adsorptive accumulation of the drug at an electrochemically treated glassy carbon electrode, followed by chronopotentiometric measurement of the surface species. The chronopotentiometric operation effectively addresses the large background contribution inherent to the glassy carbon electrode to yield a detection limit of 4 x 10(-10) M after 4 min preconcentration. The adsorptive stripping response is evaluated with respect to electrode type and conditioning, accumulation potential and lime, stripping current, pH, drug concentration, potential interferences, and other variables. Applicability to urine samples is illustrated. (C) 1997 Elsevier Science B.V.
Açıklama
Anahtar Kelimeler
tamoxifen, glassy carbon electrode, adsorptive stripping voltammetry, chronopotentiometry
Kaynak
Talanta
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
45
Sayı
2
