Çocuklarda over tümörleri
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Over tümörleri çocuklarda nadirdir. Erişkinlerin aksine germ hücreli tümörler daha sık görülürler ve bir çoğu selimdir. Bu çalışmada over tümörü saptanmış hastalar tanı, tedavi ve sonuçları yönünden incelenmiştir. Yöntem: Kliniğimizde 1984-2004 yılları arasında over tümörü saptanan 30 kız (33 over) olgunun kayıtları geriye dönük incelenmiştir. Bulgular: Hastaların yaş ortalaması 10.7±3.43 (3-18 yaş) yıldır. Onaltı hastada sol, 11 hastada sağ ve 3 hastada bilateral over tümörü saptanmıştır. Histolojik tanılar, matür teratom (n=18), immatür teratom (n=1), disgerminom (n=8), mikst germ hücreli tümör (n=1), gonadoblastom (n=1), seröz kistadenom (n=1), müsinöz kistadenom (n=2) ve granüloza hücreli tümör (n=1) olarak belirlenmiştir. Karın ağrısı (n=18), karında şişkinlik (n=11) ve kusma (n=9) en sık başvuru yakınmalarıdır. Altı hasta akut karın bulguları ile başvurmuş ve acil girişim yapılmıştır. Yirmibir salpingo-ooferektomi, 6 ooferektomi, 6 tümör eksizyonu uygulanmıştır. Habis hücre kaynaklı tümörlerde ortalama izlem süresi 84.2±47.14 (8-144 ay) aydır. Evre 4 olan tek hasta ameliyat sonrası 6. yılda nüks nedeniyle kaybedilmiş, bir hasta ise takipsizdir. Selim hücre kökenli 2 olguda sırasıyla ilk operasyondan 6 ve 55 ay sonra karşı overde aynı histolojide tümör saptanmıştır. Sonuç: Çocuklarda belirlediğimiz over kaynaklı kitlelerin büyük çoğunluğunu germ hücreli tümörler oluşturmaktadır ve bir çoğu için cerrahi tedavi yeterli olmuştur. Akut ve kronik gastrointestinal sistem yakınmalarıyla başvuran kız hastalarda adneks ve ilişkili sorunların ayırıcı tanıda dikkate alınması önem kazanmaktadır.
Aim: Tumors of the ovaries are uncommon in children. Most of them are benign and in germ cell origin, opposite to adults. In this study, children with ovarian tumors were rewieved in respect to their diagnosis, treatment and results. Method: The hospital records of 30 patients (33 ovaries) with ovarian tumors treated at our department between 1984 and 2004 were reviewed retrospectively. Results: The mean age was 10.7±3.43 (range; 3 to 18 years) years. The tumors were on the left, right and bilateral in 16, 11 and 3 patients, respectively. The histologic diagnosis of the tumors were mature teratoma (n=18), immature teratoma (n=1), dysgerminoma (n=8), mixed germ cell tumor (n=1), gonadoblastoma (n=1), serous cystadenoma (n=1), mucinous cystadenoma (n=2) and granulosa cell tumor (n=1). Abdominal pain (n=18), abdominal distention (n=11) and vomiting (n=9) were the most common symptoms. Six patients had acute abdominal findings requiring urgent surgery. The surgical procedures were salpingooophorectomy (n=21), oophorectomy (n=6), and total tumor excision with ovarian salvage (n=6). In malignant ovarian tumor group (n= 11); median fellow-up period was 84.2±47.14 months with a range of 8 to 144 months. One patient with Stage 4 tumor died 6 years later. One patient lost to follow-up in the malignant group. In two patients with diagnosis of mature cystic teratoma a new tumor was determined in the contralateral ovary with a similar histology after first operation 6th and 55th months, respectively. Conclusion: The majority of the patients had germ cell tumors in this series, and surgical treatment was all that was required for complete cure in most of them. The adnexial pathologies because of their devastating complications should be taken into consideration in differential diagnosis in young females presenting with acute or chronic gastrointestinal symptoms.
Aim: Tumors of the ovaries are uncommon in children. Most of them are benign and in germ cell origin, opposite to adults. In this study, children with ovarian tumors were rewieved in respect to their diagnosis, treatment and results. Method: The hospital records of 30 patients (33 ovaries) with ovarian tumors treated at our department between 1984 and 2004 were reviewed retrospectively. Results: The mean age was 10.7±3.43 (range; 3 to 18 years) years. The tumors were on the left, right and bilateral in 16, 11 and 3 patients, respectively. The histologic diagnosis of the tumors were mature teratoma (n=18), immature teratoma (n=1), dysgerminoma (n=8), mixed germ cell tumor (n=1), gonadoblastoma (n=1), serous cystadenoma (n=1), mucinous cystadenoma (n=2) and granulosa cell tumor (n=1). Abdominal pain (n=18), abdominal distention (n=11) and vomiting (n=9) were the most common symptoms. Six patients had acute abdominal findings requiring urgent surgery. The surgical procedures were salpingooophorectomy (n=21), oophorectomy (n=6), and total tumor excision with ovarian salvage (n=6). In malignant ovarian tumor group (n= 11); median fellow-up period was 84.2±47.14 months with a range of 8 to 144 months. One patient with Stage 4 tumor died 6 years later. One patient lost to follow-up in the malignant group. In two patients with diagnosis of mature cystic teratoma a new tumor was determined in the contralateral ovary with a similar histology after first operation 6th and 55th months, respectively. Conclusion: The majority of the patients had germ cell tumors in this series, and surgical treatment was all that was required for complete cure in most of them. The adnexial pathologies because of their devastating complications should be taken into consideration in differential diagnosis in young females presenting with acute or chronic gastrointestinal symptoms.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Çocuk Cerrahisi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
19
Sayı
2
