Communication: The Follow-Up of Biomarkers Better Predicts the Poor Outcome in COVID-19 Patients
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
NLM (Medline)
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: To investigate the course of biomarkers on admission and follow-up in order to identify early predictors for poor outcome in COVID-19 patients. METHODS: In this study, 132 COVID-19 patients were classified as good outcome (n=62) and poor outcome (n=70) groups. Laboratory parameters were evaluated on admission and within 5-7 days after hospitalization. RESULTS: Baseline levels of neutrophil-lymphocyte ratio, CRP, procalcitonin, ferritin, D-dimer and LDH were higher (p<0.01); lymphocyte count was lower in the poor outcome patients. During follow-up there was a larger decrease in lymphocyte count and more prominent increases in other biomarkers (p<0.001). In ROC analysis, the AUCs strongly indicated the poor outcome on days 5-7 of the hospitalization. CONCLUSIONS: This study suggests that the follow-up measurements of the biomarkers better predict the poor outcome in COVID-19 pneumonia. © 2020 by the Association of Clinical Scientists, Inc.
Açıklama
Anahtar Kelimeler
biomarkers, clinical outcome, COVID-19, prognosis, viral pneumonia
Kaynak
Annals of clinical and laboratory science
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
50
Sayı
6
