Quantitative and cytotoxic activity determinations on Galanthus nivalis subsp. cilicicus
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aerial and underground parts of Galanthus nivalis subsp. cilicicus, a wild-growing species in Turkey, were collected during two different vegetation periods in flowering and fruiting seasons. Herba and bulbus Galanthi were prepared from each specimen. With the aim of collecting data for prospective monographs on this drug, contents of humidity, ash, sulphated ash and total alkaloids were determined according to DAB 10. The specimens were also analyzed quantitatively for two of the principal alkaloids of the genus, galanthamine and lycorine, by using a method based on spectrophotometry complemented with TLC. LC50 values were determined for the ethanolic and alkaloidal extracts of each of the specimens using brine shrimp lethality bioassay. © 2005 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Cytotoxicity, Galanthamine, Galanthus nivalis subsp. cilicicus, Lycorine
Kaynak
Fitoterapia
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
76
Sayı
03.Apr
