An Update on Usage of High-Risk Donors in Liver Transplantation
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mdpi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The ideal management for end stage liver disease, acute liver failure, and hepatocellular carcinoma (HCC), within specific criteria, is liver transplantation (LT). Over the years, there has been a steady increase in the candidates listed for LT, without a corresponding increase in the donor pool. Therefore, due to organ shortage, it has been substantially difficult to reduce waitlist mortality among patients awaiting LT. Thus, marginal donors such as elderly donors, steatotic donors, split liver, and donors after cardiac death (DCD), which were once not commonly used, are now considered. Furthermore, it is encouraging to see the passing of Acts, such as the HIV Organ Policy Equity (HOPE) Act, enabling further research and development in utilizing HIV grafts. Subsequently, the newer antivirals have aided in successful post-transplant period, especially for hepatitis C positive grafts. However, currently, there is no standardization, and protocols are center specific in the usage of marginal donors. Therefore, studies with longer follow ups are required to standardize its use.
Açıklama
Anahtar Kelimeler
liver transplantation, steatotic donors, split liver, donors after cardiac death, HIV Organ Policy Equity (HOPE) Act, Antigen Positive Donors, Recurrent Hepatitis-C, Hepatocellular-Carcinoma, Biliary Complications, Virus-Infection, Recipients, Outcomes, Grafts, Older, Allografts
Kaynak
Journal of Clinical Medicine
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
11
Sayı
1
