The Roles of the Golgi in Various Diseases
Küçük Resim Yok
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Marmara Univ, Inst Health Sciences
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The primary function of the Golgi is to perform post-translational modifications on proteins, allow them to be transported within the cell. The Golgi has more functions in the cell, according to research into its unknown structure and functions. It has been discovered that, in addition to substance process and transport, it plays a role in autophagy, lipid formation, calcium homeostasis, and apoptosis regulation. The fact that the Golgi has so many tasks has caused question marks about what kind of illnesses or diseases it can cause in case of a problem with Golgi. A mutation at Golgi can disrupt its function by cause of the Golgi fragmentation. It can be seized by living organisms or molecules, called infectious agents, outside the mutation. Disintegration and disorders in the Golgi structure and function are examples of neurodegenerative diseases and cancer. In addition, studies prove that the SARS-CoV-2 virus, which causes pandemic in the world, is also linked to the Golgi. The diseases that can be caused by the Golgi are highlighted in this review, as are treatment studies. Treatment strategies for the Golgi that causes many diseases are still developing and studies are ongoing.
Açıklama
Anahtar Kelimeler
Golgi, Cancer, Neurodegenerative Diseases, Sars-Cov-2, Treatment
Kaynak
Clinical and Experimental Health Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
14
Sayı
1
