Neonatal short bowel syndrome as a model of intestinal failure: Physiological background for enteral feeding

Küçük Resim Yok

Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Churchill Livingstone

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Intestinal failure (IF) is a well identified clinical condition, which is characterised by the reduction of functional gut capacity below the minimum needed for adequate digestion and absorption of nutrients for normal growth in children. Short bowel syndrome (SBS) is the leading cause of IF in neonates, infants and young children usually as a result of extensive intestinal resection during the neonatal period. Simultaneously maintaining optimal nutritional status and achieving intestinal adaptation is a clinical challenge in short bowel patients. Both growth and development of the child as well as gut adaptation should be considered synergistically as primary outcome parameters. Enteral nutrition (EN) can be introduced orally and/or by tube feeding (TF). Several controversies over nutritional treatment of children with SBS related intestinal failure remain. As reported from different centres around the world, most practices are more "experienced based" rather than "evidence based". This is partly due to the small number of patients with this condition. This review (based on a consensus) discusses the physiological principles and nutritional management, including the type of diet and route of delivery. Perspectives in optimizing intestinal adaptation and reducing the consequences of small intestinal bacterial overgrowth are also discussed. (C) 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Açıklama

Anahtar Kelimeler

Short bowel syndrome, Intestinal adaptation, Enteral feeding, Oral feeding, Small intestinal bacterial overgrowth, Surgical bowel lengthening, Carbohydrates, Protein hydrolysates, Medium chain triglycerides, Amino acids

Kaynak

Clinical Nutrition

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

32

Sayı

2

Künye