The prevalence of Helicobacter pylori infection in patients with gastric and duodenal ulcers - A 10-year, single-centre experience

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Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Termedia Publishing House Ltd.

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Introduction: Helicobacter pylori (H. pylori) occurs throughout the world and causes gastroduodenal diseases. There is data indicating a change in the prevalence of H. pylori infection worldwide. The prevalence of H. pylori is 80% in Turkey, while it is higher in many developing countries, and the rate of infection varies throughout the world. In many developing countries, the prevalence of infection exceeds 90% by adulthood. Aim: To determine the change in the rate of H. pylori infection in gastric ulcers and duodenal ulcers for a 10-year period in a single centre. Material and methods: The study population included 550 patients (342 in 2004, 208 in 1994) with gastric and duodenal ulcers. Results: In 2004 there were 125 (36.5%) patients with gastric ulcer and 217 patients with duodenal ulcer (64.5%). CLO test positivity was 39.2% in patients with gastric ulcers and 60% in patients with duodenal ulcers. In 1994 there were 208 patients (159 duodenal ulcers, 49 gastric ulcers). Urease test was positive in 74.2% of patients with duodenal ulcer and in 65.2% of patients with gastric ulcer. The decrease in the rate of urease positivity in patients with gastric ulcer was statistically significant (p = 0.01) during this 10-year period. Conclusions: In the present study we found that the urease positivity decreased significantly in patients with gastric ulcer between 1994 and 2004.

Açıklama

Anahtar Kelimeler

Gastric ulcer, Helicobacter pylori, Urease test

Kaynak

Przeglad Gastroenterologiczny

WoS Q Değeri

Scopus Q Değeri

Q1

Cilt

10

Sayı

3

Künye