Effect of concentrated growth factor (CGF) on short-term clinical outcomes after partially impacted mandibular third molar surgery: A split-mouth randomized clinical study
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: the aim of this study was to evaluate the effectiveness of concentrated growth factor(CGF) on soft tissue healing and postoperative side effects following third molar surgery. Methods: This study was designed on 60 patients as a randomized single-blind clinical trial. the predictor variable was the implementation of CGF fibrin matrix, which was categorized as CGF and non-CGF. the primary outcome variable of the study was the healing of soft tissue around the extraction socket. the secondary outcome variables were pain, swelling and trismus. Data were analyzed using the non-parametric Brunner and Langer model. Statistical significance was set at P < .001. Results: Sixty patients (39 female, 21 male; mean age 25.82) with impacted mandibular third molars participated in the study. Statistical analysis revealed that there were significant differences between the control and test groups with regard to soft tissue healing, postoperative pain, swelling, and trismus (P < 0.001). Conclusion: the application of CGF accelerates soft tissue healing and is beneficial in minimising postoperative side effects, particularly pain, swelling and trismus, after extraction of mandibular third molars. (C) 2019 Published by Elsevier Masson SAS.
Açıklama
Anahtar Kelimeler
Partially impacted mandibular third molars, Concentrated growth factor, Soft tissue healing, Postoperative side effects
Kaynak
Journal of Stomatology Oral and Maxillofacial Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
121
Sayı
2
