Benzodiazepine Derivatives from Marine-DerivedStreptomyces cacaoi 14CM034
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
7-methoxy-8-hydroxy cycloanthranilylproline (2), a new natural product with pyrrolobenzodiazepine(PBD) framework, was isolated from marine-derived actinobacterium Streptomyces cacaoi 14CM034, togetherwith cycloanthranilylproline (1). Structural elucidation of the compounds was based on FTIR, 1D- (1H and 13CNMR), 2D-NMR (COSY, HMBC and NOESY) and HR-MS analyses. Compounds 1 and 2 exhibited notableantimicrobial activity. The presence of PBD derivatives in S. cacaoi was first demonstrated with this study.
Açıklama
Anahtar Kelimeler
Kaynak
Records of Natural Products
WoS Q Değeri
Scopus Q Değeri
Cilt
15
Sayı
6
