Dysphagia in Alzheimer's disease
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier France-Editions Scientifiques Medicales Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective. - To investigate electrophysiological parameters of swallowing in all stages of Alzheimer's disease. Methods. - Forty Alzheimer's disease patients, 20 age-matched normal controls and 20 young normal controls were included. Dysphagia limit (DL) and sequential water swallowing (SWS) tests were performed. Cardiac rhythm, respiration and sympathetic skin responses were concomitantly recorded. Results. - Dysphagia was found in 30/40 (75%) of Alzheimer's disease patients. Mean volume at the DL test was significantly reduced (16.5 +/- 1.0 mL) in the Alzheimer's disease group. Swallowing and apnea times in the SWS test were significantly prolonged in elderly controls, but even longer in Alzheimer's disease patients. Conclusions. - Alzheimer's disease patients had electrophysiological features of dysphagia, even in the early period of disease. The cortical involvement and severity of cognitive disorder can increase swallowing problems, but subclinical signs of dysphagia may be observed even in patients with mild or moderate Alzheimer's disease. (C) 2016 Elsevier Masson SAS. All rights reserved.
Açıklama
Anahtar Kelimeler
Alzheimer's disease, Deglutition, Dementia, Electrophysiology, Swallowing
Kaynak
Neurophysiologie Clinique-Clinical Neurophysiology
WoS Q Değeri
Q3
Scopus Q Değeri
Cilt
46
Sayı
3
