Electrochemical Determination of Homocysteine at Disposable Graphite Electrodes
Küçük Resim Yok
Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In the case of disruption of Hcy metabolism, the blood level of Hcy increases and it causes particularly the cardiovascular diseases, cancer, dementia and Parkinson's disease. Thus, the sensitive analysis of Hcy levels in biological fluids is very important. Hcy analysis was performed herein using very practical and cost-effective protocol using differential pulse voltammetry and graphite electrode. Detection limit of Hcy was found to be 1.21 mu M in the linear range from 2 mu M to 20 mu M. The electrochemical Hcy detection in artificial urine medium was also successfully performed even in the presence of L-Cysteine, L-Methionine and Glutathione.
Açıklama
Anahtar Kelimeler
Homocysteine, Direct electrochemical detection, Protein, Urine, Pencil graphite electrode
Kaynak
Electroanalysis
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
26
Sayı
9
