An analytical approach based on ESI-MS, LC-MS and PCA for the quail-quantitative analysis of cycloartane derivatives in Astragalus spp.
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Astragalus species are widely used as health foods and dietary supplements, as well as drugs in traditional medicine. To rapidly evaluate metabolite similarities and differences among the EtOH extracts of the roots of eight commercial Astragalus spp., an approach based on direct analyses by ESI-MS followed by PCA of ESI-MS data, was carried out. Successively, quali-quantitative analyses of cycloartane derivatives in the eight Astragalus spp. by LC-ESI-MSn and PCA of LC-ESI-MS data were performed. This approach allowed to promptly highlighting metabolite similarities and differences among the various Astragalus spp. PCA results from LC-ESI-MS data of Astragalus samples were in reasonable agreement with both PCA results of ESI-MS data and quantitative results. This study affords an analytical method for the quali-quantitative determination of cycloartane derivatives in herbal preparations used as health and food supplements. (C) 2013 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Astragalus genus, Cycloartanes, ESI-MS, LC-ESI-MS, PCA
Kaynak
Journal of Pharmaceutical and Biomedical Analysis
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
85
