Determination of phytochemical contents by LC/ QTOF/MS and evaluation of in-vitro biological activities of 2 Peltigera lichens from Bursa
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Acad Brasileira De Ciencias
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Lichens are symbiotic associations of algae and fungi. They are edible as food and have been used in traditional medicine for years. It is aimed to screen phytochemically by LC/QTOF/MS and according to the constituents to evaluate the antioxidant, tyrosinase inhibitory, and antibacterial activities. In total 54 of metabolites detected by LC/QTOF/MS were common in both species. According to LC/QTOF/MS scanning results, alkaloids, iridoid glycosides, phenolics, cyanogenetic glycosides, and terpenic structures were detected. DPPH, ABTS, superoxide radical scavenging activities, and metal chelating capacity IC50 values were 84.55, 9.349; 51.27, 9.127; 95.01, 58.65 and 20.57, 70.08 mu g/mL., respectively. The CUPRAC reducing power was determined as 4.69 and 9.57 TEACCUPRAC, respectively. Tyrosinase inhibitor activity were found to be 86.95 and 196.7 mu g/mL. Both lichens did not show antimicrobial effects. As a result of the antioxidant and tyrosinase inhibitor activities it was seen that their activities were significant and further in vivo studies could be carried out on this lichens.
Açıklama
Anahtar Kelimeler
Antioxidant, Lc/Qtof/Ms, Lichen Phenolics, Peltigera Elisabethae Gyeln., Peltigera Praetextata (Fl & Ouml;Rke Ex Sommerf.), Tyrosinase Inhibitor
Kaynak
Anais Da Academia Brasileira De Ciencias
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
96
Sayı
2