Targeted Alpha Radionuclide Therapy (TAT)-Ac-225 Radiopharmaceuticals; [Hedefe Yönelik Alfa Radyonüklid Tedavisi (TAT)-Ac-225 Radyofarmasötikleri]

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Galenos Publishing House

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Targeted alpha therapy (TAT) has become increasingly popular in recent years due to its easy application in patients with multiple metastases, its ability to treat multiple lesions simultaneously, and its ability to be used in combination with other treatment methods. TAT is performed by chelate conjugated-targeting molecules such as small peptides, peptidomimetics, monoclonal antibodies, biomolecules and small inhibitor molecules tagged with alpha-emiting radionuclides. It is possible to obtain Actinium-225 in various ways. The majority of Ac-225 used for preclinical research and clinical administration is radiochemically isolated from build-up sources of thorium-229. © 2023 The authors.

Açıklama

Anahtar Kelimeler

Ac-225, Ac-225 radiopharmaceuticals, Targeted alpha therapy

Kaynak

Nuclear Medicine Seminars

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

9

Sayı

1

Künye