Ultrastructural morphology and pathogenesis in Alzheimer's disease
Küçük Resim Yok
Tarih
1975
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Biopsy specimens of the cerebral cortex from two histologically confirmed cases of Alzheimer's disease were examined by means of electron microscopy. The senile plaques consisted of a complex of abnormal dendrites, axons and extracellularly located amyloid. Alzheimer's neurofibrillary tangles were made of bundles of filaments in the pericaryon. Amyloid in the plaques and in the liver showed the same ultrastructural morphology. A suggestion is made that the changes observed at the synaptic level are possibly responsible for memory defects in the disease. No evidence was found to suggest any viral or vascular aetiology in the disease. (Journal received: 18 January 1977)
Açıklama
Anahtar Kelimeler
Kaynak
Aegean Medical Journal
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
4
Sayı
1
