A longitudinal study of lateral ventricle volumes in deficit and non-deficit schizophrenia
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Although it is generally accepted that negative symptoms of schizophrenia are associated with larger lateral ventricles, this general assumption could not be validated in patients with primary negative symptoms. To elucidate this issue, we conducted a five-year longitudinal study, including deficit (n = 13) and non-deficit (n = 26) schizophrenia patients with healthy controls (n = 18). Analysis with linear mixed effects modeling showed that both the left and the right lateral ventricles of the deficit patients enlarged more than the non-deficit patients. Our results suggest that structural alterations in deficit patients might follow a different trajectory than those in non-deficit patients.
Açıklama
Anahtar Kelimeler
Psychotic disorders, Primary negative symptoms, Structural MRI, Follow-up, Linear mixed effects model, Progressive Brain Changes, Structural Abnormalities, Mri, Segmentation, Patterns, Regions
Kaynak
Psychiatry Research-Neuroimaging
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
313
