Stem Cells as a Promising Tool for the Restoration of Brain Neurovascular Unit and Angiogenic Orientation
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Establishing systemic therapeutics for neuro-inflammatory diseases is a main objective of regenerative medicine, certainly focusing on restoration of BBB dysfunction and neurovascular reconstitution. In this context, the regenerative capacity and therapeutic effects of different stem cells have been recently found to bring hopeful outcomes through trans-differentiation, paracrine interactions, and molecular cross-talk of transplanted stem cells with resident cells of blood-brain barrier. Here, we highlight some of the most recent scientific breakthroughs and discoveries by different authorities. Potency of different types of stem cells on the regulation and maintenance of endothelial and perivascular cells via various microRNAs was also studied.
Açıklama
Anahtar Kelimeler
Stem cell, Brain neurovascular unit, Trans-differentiation, Paracrine behavior, MicroRNAs
Kaynak
Molecular Neurobiology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
54
Sayı
10
