Bioequivalency evaluation by comparison of in vitro dissolution and in vivo absorption using reference equations
Küçük Resim Yok
Tarih
1994
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Using in vitro dissolution and in vivo absorption of different generics or batches for an appropriate drug and dosage form, a reference equation of form: {Mathematical expression} can be proposed. In the case of availability of standardised in vitro-in vivo data for a specific drug, a Level A a correlation of this type containing experimentally determined a, b, d parameters would serve to predict in vivo absorption phase of the drug. The larger number of batches, the stronger will be the predictive power of these parameters. © 1994 Springer-Verlag.
Açıklama
Anahtar Kelimeler
bioavailability, Bioequivalency, carbamazepine, in vitro-in vivo correlation, pharmacokinetics
Kaynak
European Journal of Drug Metabolism and Pharmacokinetics
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
19
Sayı
3
