1996-1998 yılları yaz dönemindeki ishalli olgularda Salmonella ve Shigella prevalansı ve antimikrobik duyarlılıkları
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
1996-1998 yılları arasında ishal yakınması ile başvuran 117 olgunun dışkı direkt mikroskopik bakısında 57 (%48.7) olguda lökosit ve eritrosit, 34 (%29) olguda lökosit ve 2 (% 1.7) olguda eritrosit görülmüştür. Dışkı kültürlerinde 12 (%10) olguda Shigella spp, sekiz (%6.8) olguda ise Salmonella serotipleri üremiştir. Shigella türlerinde ampisilin, amoksasilin klavulanik asit, kloramfenikol, TMP-SMX, gentamisin ve seftriaksona karşı direnç sırasıyla %58, %50, %33, %58, %25, %8 iken bu değerler Salmonella serotiplerinde %75, %50, %37.5, %12.5, %12.5 olarak bulunmuştur. Ofloksasine karşı direnç saptanmamıştır. Sonuç olarak, kinolonların antimikrobiyal tedavinin gerektiği ishallerde ampirik olarak güvenle kullanılabileceği kanısına varılmıştır.
The aim of this study was to determine the prevalence of Salmonella and Shigella in cases of diarrhea and also the drgs(s) of choice for empiric therapy. In the examination of feces sample of a hundred seventeen patients with diarrhea complaint, leucocyte and erythrocyte in 57 (48.7%), leucocyte in 34 (29%) and erythrocyte in 2 (1.7%) were seen in the 1996-1998 period. In the stool culture 10% Shigella species and 6.8% Salmonella serotypes were isolated. Resistance to ampicillin, amoxacillin-clavulanic acid, chloramphenicol, TMP-SMX, gentamycin and cephtriaxon were seen as 58%, 50%, 33%, 58%, 25% and 8% for Shigella species and 75%, 50%, 37.5%, 12.5%, 12.5% for Salmonella serotypes, respectively. Quinolon resistance was not found. In conclusion, quinolons can be safely used ampirically when antimicrobial therapy is needed for diarrheal diseases.
The aim of this study was to determine the prevalence of Salmonella and Shigella in cases of diarrhea and also the drgs(s) of choice for empiric therapy. In the examination of feces sample of a hundred seventeen patients with diarrhea complaint, leucocyte and erythrocyte in 57 (48.7%), leucocyte in 34 (29%) and erythrocyte in 2 (1.7%) were seen in the 1996-1998 period. In the stool culture 10% Shigella species and 6.8% Salmonella serotypes were isolated. Resistance to ampicillin, amoxacillin-clavulanic acid, chloramphenicol, TMP-SMX, gentamycin and cephtriaxon were seen as 58%, 50%, 33%, 58%, 25% and 8% for Shigella species and 75%, 50%, 37.5%, 12.5%, 12.5% for Salmonella serotypes, respectively. Quinolon resistance was not found. In conclusion, quinolons can be safely used ampirically when antimicrobial therapy is needed for diarrheal diseases.
Açıklama
Anahtar Kelimeler
Enfeksiyon Hastalıkları
Kaynak
İnfeksiyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
13
Sayı
3
