Investigation of DNA-magnetic nanoparticle interaction by magneto-optical linear dichroism

In this study, interaction of produced magnetic nanoparticles (MNPs) with DNA was investigated by using designed magneto-optical linear dichroism (MOLD) measurement system. Fe3O4 nanoparticles (NPs), produced by using co-precipitation method were characterized by means of structure, magnetic, and size distribution. These NPs coated with oleic acid and Tetramethylammoniumhydroxide (TMA) in water and ethanol. Change of the linear dichroism property of dissolved NPs in the fluid under applied magnetic field was observed due to the interaction of produced MNPs with DNA. Obtained results were shown that it is possible to develop a DNA sensor by using MNPs and MOLD effect.