An insidious disaster composed of sinusitis, myocarditis, lung mass and rapidly progressive glomerulonephritis: Wegener granulomatosis
Küçük Resim Yok
Tarih
2010
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Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Wegener granulomatozu klasik olarak alt ve üst hava yolları, böbrekler, deri ve eklemleri etkileyen nekrotizan granülomatoz yangılı vaskülitik sendromdur. Bir çok organ etkilenebileceğinden tutulan organa bağlı heterojen klinik bulgu verme özelliği vardir. Özgün olmayan sistemik klinik bulgular eşliğinde bazen, sadece klinisyenin şüphesi ile tanı konulabilir. Burada, genel durum bozukluğu, ateş, klinik kalp yetmezliği ve akciğerde kitle tanısı ile izlenen ve takipte akut böbrek yetmezliği gelişen Wegener Granulomatozlu bir hasta sunulmuştur. Multidisipliner yaklaşım tanı ve tedavide önemlidir. Akut vaskülit sendromların özellikle şiddetli böbrek dışı tutuluşlarında sitotoksik tedavi ve/veya plazma değişimi hayat kurtarıcı olabilir.
Wegener's Granulomatosis is a multisystemic granulomatous inflammation of small vessels that typically effects the kidney, skin, joints and lower and upper airway tracts. Because of the multisystemic involvement, the signs and symptoms of disease may arise in heterogeneous fashion. Under the appearance of a nonspecific sytemic complaints, the suspicion of clinician may be a final clue for diagnosis. Here we present a patient with Wegener's granolomatosis sufferring from generalized malaise, fever, heart failure, lung mass and acute renal failure. Multidisciplinary and close colloborative management is important to establish early diagnosis. We belive that plasmapheresis at initial acute onset of vasculitis syndromes especially in severe extrarenal involvements may be a lifesaving management.
Wegener's Granulomatosis is a multisystemic granulomatous inflammation of small vessels that typically effects the kidney, skin, joints and lower and upper airway tracts. Because of the multisystemic involvement, the signs and symptoms of disease may arise in heterogeneous fashion. Under the appearance of a nonspecific sytemic complaints, the suspicion of clinician may be a final clue for diagnosis. Here we present a patient with Wegener's granolomatosis sufferring from generalized malaise, fever, heart failure, lung mass and acute renal failure. Multidisciplinary and close colloborative management is important to establish early diagnosis. We belive that plasmapheresis at initial acute onset of vasculitis syndromes especially in severe extrarenal involvements may be a lifesaving management.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
19
Sayı
1
