Kolandik epilepsili olguların değerlendirilmesi
Küçük Resim Yok
Tarih
1995
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Yirmiiki rolandik epilepsili olgu retrospektif olarak değerlendirilmiştir. Olguların ilk nöbet yası 3-14 (7±2.7) yaş arasında değişmekte olup %46'sı kızdır. Gözlenen nöbetlerin %72'si uyku ile ilişkilidir, tik nöbetler fokal (%46),jeneralize (%36) veya sekonder jeneralize (%18) özelliktedir, tik EEG'de iki olguda bilateral, diğerlerinde tek taraflı santral veya midtemporal foküs saptanmıştır. Tüm olgularda karbamaze-pin, difenilhidantoin veya fenobarbital şeklinde tek antikonvülsan ilaçla tedavi başlanmış, dört olguda düzenli ilaç kullanımına rağmen çok sık nöbet tekrarı gözlenmiş, iki olguda antikonvülsan ilaç değişikliği yapılmıştır. Onsekiz olguda nöbetsiz geçen 24-64 (345±13.8) ay sonra tedavi kesilmiştir. Tedavi kesilmeden önce çekilen EEG'lerde üç olgu dışında foküs aktivitesinin düzeldiği gözlenmiştir. Tedavi kesilirken ve kesildikten 1.5 yıl sonra yalnız iki olguda nöbet tekrarı gözlenmiş ve tedaviye yeniden başlanmıştır. Bu olguların EEG'lerinde halen foküs aktivitesinin sürdüğü dikkati çekmiştir.
Twenty two patients with rolandic epilepsy were evaluated retrospectively. First seizure was observed between 3- 14 (7±2.7) years, 46% of the patients female. 72% of observed seizures were related with sleep. Clinical evaluation revealed that first seizures ocal (46%), generalized (36%) and secondary generalized (18%). All but two patients had unilateral central or temporal epileptic focus on their first EEG. Single anticonvulsant drug like carbamazepine, diphenylhydantoin, phenobarbital was given to all patients. Four patients suffered from very frequent seizures despite the regular anticonvulsant treatment. In two of them anticonvulsant therapy was changed with positive result. In 18 patients, anticonvulsant drugs were tapered off within 6 months following 24-64 (345±13.8) months of seizure free period. EEG obtained before discontinuing therapy revealed that three patients still had focus activity. Only two patients had recurrent seizures during tapering off drugs, anticonvulsant therapy was resumed for them. It was interesting to note that they had still focus activity on their EEG.
Twenty two patients with rolandic epilepsy were evaluated retrospectively. First seizure was observed between 3- 14 (7±2.7) years, 46% of the patients female. 72% of observed seizures were related with sleep. Clinical evaluation revealed that first seizures ocal (46%), generalized (36%) and secondary generalized (18%). All but two patients had unilateral central or temporal epileptic focus on their first EEG. Single anticonvulsant drug like carbamazepine, diphenylhydantoin, phenobarbital was given to all patients. Four patients suffered from very frequent seizures despite the regular anticonvulsant treatment. In two of them anticonvulsant therapy was changed with positive result. In 18 patients, anticonvulsant drugs were tapered off within 6 months following 24-64 (345±13.8) months of seizure free period. EEG obtained before discontinuing therapy revealed that three patients still had focus activity. Only two patients had recurrent seizures during tapering off drugs, anticonvulsant therapy was resumed for them. It was interesting to note that they had still focus activity on their EEG.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
3
