Palladium-EDTA and palladium-EdteH 4 catalyzed Heck coupling reactions in pure water
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Tarih
2013
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N, N, N ′ , N ′ -tetrakis(2-hydroxyethyl)ethylenediamine (EdteH 4 ) and ethylenediaminetetraacetic acid disodium salt (Na 2 EDTA) as ligands. The effect of different bases, catalyst loading, and additives is also monitored. The olefination of bromoarenes with styrene affords the desired products in high yields. The Na 2 PdCl 4 - Na 2 EDTA precatalyst system is also used for the preparative scale (50.0 mmol) synthesis of 4-acetyl-trans-stilbene and 4-styrylbenzaldehyde without a noticeable decrease in the activity. Recycling studies on the Na 2 PdCl 4 - Na 2 EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.
Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N, N, N ′ , N ′ -tetrakis(2-hydroxyethyl)ethylenediamine (EdteH 4 ) and ethylenediaminetetraacetic acid disodium salt (Na 2 EDTA) as ligands. The effect of different bases, catalyst loading, and additives is also monitored. The olefination of bromoarenes with styrene affords the desired products in high yields. The Na 2 PdCl 4 - Na 2 EDTA precatalyst system is also used for the preparative scale (50.0 mmol) synthesis of 4-acetyl-trans-stilbene and 4-styrylbenzaldehyde without a noticeable decrease in the activity. Recycling studies on the Na 2 PdCl 4 - Na 2 EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.
Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N, N, N ′ , N ′ -tetrakis(2-hydroxyethyl)ethylenediamine (EdteH 4 ) and ethylenediaminetetraacetic acid disodium salt (Na 2 EDTA) as ligands. The effect of different bases, catalyst loading, and additives is also monitored. The olefination of bromoarenes with styrene affords the desired products in high yields. The Na 2 PdCl 4 - Na 2 EDTA precatalyst system is also used for the preparative scale (50.0 mmol) synthesis of 4-acetyl-trans-stilbene and 4-styrylbenzaldehyde without a noticeable decrease in the activity. Recycling studies on the Na 2 PdCl 4 - Na 2 EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.
Açıklama
Anahtar Kelimeler
Mühendislik, Kimya
Kaynak
Turkish Journal of Chemistry
WoS Q Değeri
Scopus Q Değeri
Cilt
37
Sayı
5
