Two siblings with triple-a syndrome: Endocrinologic and neurologic features [Triple A Sendromlu iki Kardeş: Endokrinolojik ve Nörolojik özellikler]

Triple-A syndrome is a rare, multi-systemic disease and is characterized by adrenal insufficiency, achalasia, or alacrima. The symptoms may also involve neurologic manifestations, including pyramidal findings and peripheral motor neuropathy. Other findings include autonomic dysfunction and cerebellar ataxia. In the present study, we present the case of two siblings with triple-A syndrome with neurologic manifestations. The neurologic abnormalities can lead to misdiagnosis owing to resemblance to the manifestations of other neurologic disorders. Therefore, the cases with tripleA syndrome should be carefully evaluated and examined for clinical and neurophysiologic signs. © 2018 by Turkish Journal of Endocrinology and Metabolism Association.