Keratoconus and Fuchs' heterochromic iridocyclitis: a coincidence or a defect during embryogenesis?
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wichtig Editore
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
PURPOSE. We aimed to discuss the possible role of developmental embryologic factors in neural crest cells in the aetiology of keratoconus and Fuchs' heterochromic iridocyclitis by presenting this case. CASE REPORT. We diagnosed bilateral keratoconus and unilateral Fuchs' heterochromic iridocyclitis in a 19 year old women complaining of progressively blurring vision in her left eye. We also examined most of her first and second degree relatives. One niece had FHI in addition to a choroidal nevus in the inferior temporal quadrant of her left eye. DISCUSSION. Regarding the common embryological origins of iris stroma, uveal melanocytes and corneal stroma, it might be worth considering that the combination of FHI and keratoconus is not coincidental. A role of embryologic factors in neural crest cells in the etiology of both diseases cannot be excluded.
Açıklama
Anahtar Kelimeler
keratoconus, Fuchs' heterochromic iridocyclitis, etiology, embryogenesis
Kaynak
European Journal of Ophthalmology
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
11
Sayı
1
