Spatial Smoothing Effect on Group-Level Functional Connectivity during Resting and Task-Based fMRI
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Multidisciplinary Digital Publishing Institute (MDPI)
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Spatial smoothing is a preprocessing step applied to neuroimaging data to enhance data quality by reducing noise and artifacts. However, selecting an appropriate smoothing kernel size can be challenging as it can lead to undesired alterations in final images and functional connectivity networks. However, there is no sufficient information about the effects of the Gaussian kernel size on group-level results for different cases yet. This study investigates the influence of kernel size on functional connectivity networks and network parameters in whole-brain rs-fMRI and tb-fMRI analyses of healthy adults. The analysis includes {0, 2, 4, 6, 8, 10} mm kernels, commonly used in practical analyses, covering all major brain networks. Graph theoretical measures such as betweenness centrality, global/local efficiency, clustering coefficient, and average path length are examined for each kernel. Additionally, principal component analysis (PCA) and independent component analysis (ICA) parameters, namely kurtosis and skewness, are evaluated for the functional images. The findings demonstrate that kernel size directly affects node connections, resulting in modifications to functional network structures and PCA/ICA parameters. However, network metrics exhibit greater resilience to these changes. © 2023 by the author.
Açıklama
Anahtar Kelimeler
connectivity analysis, fMRI, full-width half maximum (FWHM), functional connectivity (FC), gaussian kernel, resting state, smoothing effect, spatial smoothing, task-based fMRI, Graph theory, Higher order statistics, Principal component analysis, Connectivity analysis, FMRI, Full width half maximum, Full-width half maximum, Functional connectivity, Gaussian kernels, Resting state, Smoothing effects, Spatial smoothing, Task-based, Task-based fMRI, Independent component analysis, adult, brain, brain mapping, diagnostic imaging, human, neuroimaging, nuclear magnetic resonance imaging, procedures, rest, Adult, Brain, Brain Mapping, Humans, Magnetic Resonance Imaging, Neuroimaging, Rest
Kaynak
Sensors
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
23
Sayı
13
