Amniotic fluid odd-chain fatty acids are increased in propionic acidaemia
Küçük Resim Yok
Tarih
1996
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
John Wiley & Sons Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Odd-chain (C-15 and C-17) fatty acids have been reported to accumulate in tissues and body fluids of patients with propionic and methylmalonic acidaemia. We investigated the occurrence of these substances in amniotic fluid samples. The odd-chain fatty acid levels (expressed as the percentage of total C-12-C-20 fatty acids) in eight control samples ranged from 3.7 to 12.5 per cent. Three samples from affected propionic acidaemia pregnancies had values of 15.3-22.9 per cent; one methylmalonic acidaemia sample had a normal level of 9.3 per cent. These results supply further evidence of the prenatal accumulation of odd-chain fatty acids in propionic acidaemia.
Açıklama
Anahtar Kelimeler
amniotic fluid, odd-chain fatty acids, propionic acidaemia
Kaynak
Prenatal Diagnosis
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
16
Sayı
10
