Evaluation of antimicrobial activities of some 2(3H)-benzoxazolone derivatives
Küçük Resim Yok
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, 12 w-(2-oxo-2-benzoxazoline-3-yl)-N-phenylacetamide and propionamide derivatives bearing substituents with different lipophilic and electronic nature on N-phenyl ring were tested for antimicrobial activity. For this purpose, minimal effective concentrations of the compounds were determined against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans by using microdilution method. The results demonstrated that 3-(2-oxo-2-benzoxazoline-3-yl)-N-(m-tolyl)propionamide derivative was the most active compound in the series against Escherichia coli, Staphylococcus aureus and Enterococcus faecalis.
Açıklama
Anahtar Kelimeler
2(3H)-Benzoxazolone, Amide, Antimicrobial activity, Synthesis
Kaynak
Fabad Journal of Pharmaceutical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
32
Sayı
4
