Acceptorless Dehydrogenative Oxidation of Secondary Alcohols Catalysed by Cp*Ir-III-NHC Complexes
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A series of new Ir-III complexes with carbene ligands that contain a range of benzyl wingtip groups have been prepared and fully characterised by NMR spectroscopy, HRMS, elemental analysis and X-ray diffraction. All the complexes were active in the acceptorless dehydrogenation of alcohol substrates in 2,2,2-trifluoroethanol to give the corresponding carbonyl compounds. The most active complex bore an electron-rich carbene ligand; this complex was used to catalyse the highly efficient and chemoselective dehydrogenation of a wide range of secondary alcohols to their respective ketones, with turnover numbers up to 1660. Mechanistic studies suggested that the turnover of the dehydrogenation reaction is limited by the H-2-formation step.
Açıklama
Anahtar Kelimeler
acceptorless dehydrogenation, alcohols, carbenes, iridium, oxidation
Kaynak
Chemistry-A European Journal
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
22
Sayı
30
