Alginate as an immobilization material for MAb production via encapsulated hybridoma cells
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Alginate has been widely used in various applications since its first extraction. What makes this biopolymer useful is its high biocompatibility and humid gelation conditions. Both of these features bring it into prominence as an ideal immobilization material. However, there are some complicated aspects of cell immobilization using alginate biopolymers. This review discuses and clarifies these crucial points, using as an example the bioprocessing of highly fragile cells (hybridoma cells). The review focuses on the cultivation and production of alginate encapsulated cells.
Açıklama
Anahtar Kelimeler
Alginate, immobilization, hybridoma, monoclonal antibody production
Kaynak
Critical Reviews in Biotechnology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
30
Sayı
2
