Sustained-release dosage form of phenylpropanolamine hydrochloride. Part I: Microencapsulation and in vitro release kinetics
Küçük Resim Yok
Tarih
1994
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Informa Healthcare
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Microcapsules of phenylpropanolamine hydrochloride with core wall ratios of 1: 1,2: 1 and 1 2 were prepared by the coacervation-phase separation method, using ethylcellulose as the coating material. Two batches of PPA.HC1 powder with different particle sizes (< 58µm and > 28µm) were used as the core material. The different sizes of microcapsules were separated using a range of standard sieves (840-247µm). The effects of drug particle size, the media pH and the core: wall ratio on the dissolution kinetics were studied, and evaluated kinetically. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
Açıklama
Anahtar Kelimeler
Kaynak
Journal of Microencapsulation
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
11
Sayı
3