Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada sık solunum yolu enfeksiyonu geçiren, rutubetli evlerde yaşayan çocuklarda polen, akar ve küf duyarlılıkları ince- lendi ve ebeveynlerin ayrılığı, eğitim durumu, etnik köken, kardeş sahibi olma ve kardeşlerin atopi durumunun atopi gelişimi üzerindeki etkileri değerlendirildi. Hastalar ve Yöntemler: Haziran 2012 - Eylül 2013 tarihleri arasında Acıbadem Bodrum hastanesine küf maruziyeti ile yılda en az altı solunum yolu enfeksiyonu (SYE) ve uzamış öksürük atakları ile başvuran ve deri prick testi yapılan 63 çocuk (28 kız, 35 erkek; ort. yaş 80.2 ay; dağılım 24-97 ay) çalışmaya dahil edildi. Deri prick testi pozitif (DTP) olan hastalar alt solunum yolu (ASY) veya üst solunum yolu (ÜSY) tutulumlarına göre gruplandırıldı ve küf, akar ve polen duyarlılık durumları incelendi. Bulgular: Hastaların üçte birinde DTP saptandı. Bu hastaların ebeveynlerinde yüksek oranda doktor tanılı alerji varlığı izlendi (p<0.05). Akar duyarlılığı olan hastaların büyük bir kısmında ASY ve ÜSY bulguları vardı (p<0.05). Polen duyarlılığı olan hastalarda ÜSY bulguları daha hakimdi (p<0.05). Küf duyarlılığı olan çocukların tamamında ASY bulguları izlendi (p<0.05). Sonuç: Atopik olmayan çocuklara kıyasla, atopik çocuklarda küf maruziyeti ile ASY semptomlarına daha sık rastlanabilir. Ayrıca küf maruziyeti, immünoglobulin E bağımlı duyarlılaşmaya neden olmaksızın, ASY enflamasyonuna yol açabilir.
Objectives: This study aims to investigate pollen, mite and mold sensitivities among children with frequent respiratory tract infection living in damp apartments and to evaluate the effects of separated parents, education status, ethnicity, the presence of siblings, and their atopy status on the development of atopy. Patients and Methods: Between June 2012 and September 2013, 63 children (28 girls, 35 boys; mean age 80.2 years; range 24 to 97 years) who were admitted to Acıbadem Bodrum Hospital with at least six respiratory tract infection per year with mold exposure and prolonged cough attacks and underwent skin prick test (SPT) were included. Skin prick test-positive patients were further divided into groups according to the upper respiratory tract (URT) or lower respiratory tract (LRT) involvement and were assessed for mold, mite and pollen sensitivities. Results: One-third of the patients were SPT positive. The parents of these patients had physician-diagnosed allergy (p<0.05). Most patients with mite sensitivity presented with URT and LRT findings (p<0.05). Pollen-sensitive patients had predominantly URT findings (p<0.05). All children with mold sensitivity presented with LRT findings (p<0.05). Conclusion: Atopic children may experience more frequent LRT symptoms when exposed to molds than non-atopic children. Mold exposure may also cause inflammation at LRT without causing immunoglobulin E-dependent sensitization.
Objectives: This study aims to investigate pollen, mite and mold sensitivities among children with frequent respiratory tract infection living in damp apartments and to evaluate the effects of separated parents, education status, ethnicity, the presence of siblings, and their atopy status on the development of atopy. Patients and Methods: Between June 2012 and September 2013, 63 children (28 girls, 35 boys; mean age 80.2 years; range 24 to 97 years) who were admitted to Acıbadem Bodrum Hospital with at least six respiratory tract infection per year with mold exposure and prolonged cough attacks and underwent skin prick test (SPT) were included. Skin prick test-positive patients were further divided into groups according to the upper respiratory tract (URT) or lower respiratory tract (LRT) involvement and were assessed for mold, mite and pollen sensitivities. Results: One-third of the patients were SPT positive. The parents of these patients had physician-diagnosed allergy (p<0.05). Most patients with mite sensitivity presented with URT and LRT findings (p<0.05). Pollen-sensitive patients had predominantly URT findings (p<0.05). All children with mold sensitivity presented with LRT findings (p<0.05). Conclusion: Atopic children may experience more frequent LRT symptoms when exposed to molds than non-atopic children. Mold exposure may also cause inflammation at LRT without causing immunoglobulin E-dependent sensitization.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Kulak Burun Boğaz İhtisas Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
24
Sayı
4
