Thioguanine-Related Chronic Hepatotoxicity in a Child with Acute Myeloid Leukemia: A Case Report and Review

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Galenos Yayincilik

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The association between 6-Thioguanine (6-TG) treatment and drug-induced liver injury has been reported since 1976. Recent reports have suggested that treatment of patients with 6-TG can lead to chronic hepatotoxicity and portal hypertension. Most of the cases reported to have 6-TG related hepatotoxicity had acute lymphoblastic leukemia or inflammatory bowel disease. In this case report, we discussed the diagnosis and approach in an acute myeloid leukemia patient who developed 6-TG related chronic hepatotoxicity.

Açıklama

Anahtar Kelimeler

6-Thioguanine, hepatotoxicity, leukemia

Kaynak

Journal of Pediatric Research

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

2

Sayı

2

Künye