Fish Oil Derivatives in Hypertriglyceridemia: Mechanism and Cardiovascular Prevention: What Do Studies Say?
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Hypertriglyceridemia is a type of dyslipidemia characterized by high triglyceride levels in the blood and increases the risk of cardiovascular disease. Conventional management includes antilipidemic medications such as statins, lowering LDL and triglyceride levels as well as raising HDL levels. However, the treatment may be stratified using omega-3 fatty acid supplements such as eicosatetraenoic acid (EPA) and docosahexaenoic acid (DHA), aka fish oil derivatives. Studies have shown that fish oil supplements reduce the risk of cardiovascular diseases; however, the underlying mechanism and the extent of reduction in CVD need more clarification. Our paper aims to review the clinical trials and observational studies in the current literature, investigating the use of fish oil and its benefits on the cardiovascular system as well as the proposed underlying mechanism. © 2023 Elsevier Inc.
Açıklama
Anahtar Kelimeler
docosahexaenoic acid, hydroxymethylglutaryl coenzyme A reductase inhibitor, icosapentaenoic acid ethyl ester, icosatetraenoic acid, low density lipoprotein cholesterol, triacylglycerol, cardiovascular risk, drug activity, drug effect, drug efficacy, drug mechanism, follow up, human, hypertriglyceridemia, inflammation, lipid fingerprinting, lipid metabolism, Review, risk reduction
Kaynak
Current Problems in Cardiology
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
49
Sayı
1
