An indirect lectin affinity bioassay for uromodulin
Küçük Resim Yok
Tarih
2002
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Scientific Technical Research Council Turkey
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Uromodulin is a monomeric glycoprotein excreted in large amounts in urine. Most of the assay methods for quantifying uromodulin rely on the availability of antibodies to this glycoprotein. This study reports a new bioassay for uromodulin without requiring the presence of antibodies. The bioassay is based on the lectin affinity of the glycoprotein and the known interaction between uromodulin and the tumor necrosis factor. The measuring range of the bioassay described in this paper is between 0.13 and 1.25 mug/ml, which makes it a potential method for clinical use.
Açıklama
Anahtar Kelimeler
glycoprotein, methods, biological assay
Kaynak
Turkish Journal of Chemistry
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
26
Sayı
3
