Yazar "Yilmaz, F." seçeneğine göre listele
Listeleniyor 1 - 20 / 30
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Characteristics of steatohepatitic hepatocellular carcinoma in a series of predominantly virus-related cirrhosis(Springer, 2013) Aykutlu, U.; Uguz, A.; Unalp, O.; Nart, D.; Karasu, Z.; Sozbilen, M.; Yilmaz, F.Öğe Ciliated hepatic foregut cyst: Report of four cases and review of the literature(Springer, 2017) Erbil, S.; Ergun, O.; Yilmaz, F.; Nart, D.Öğe Correlation of immunohistochemistry on liver biopsy and serum HBVDNA levels(Elsevier Science Bv, 2008) Yilmaz, F.; Nart, D.; Vardar, R.; Gunsar, F.; Ersoz, G.; Karasu, Z.; Sertoz, R.; Erensoy, S.; Ilter, T.; Batur, Y.; Akarca, U. S.Öğe Effects of different storage media on dentin moisture, microhardness, and bond strength of resin composite(NLM (Medline), 2023) Yilmaz, F.; Guvenc, P.; Pamir, T.; Demirbas, A.; Sen, B.H.Background: In in vitro studies, it is desirable that the storage solutions in which dental samples kept between extraction and experiment should prevent dehydration and have antimicrobial properties. However, it should be taken into consideration that these solutions may have some effects that directly change test results on physical and mechanical properties of laboratory samples. Aims: The aim of this in vitro study was to evaluate the effects of different storage media on dentin moisture, microhardness, and microshear bond strength of resin composite to dentin. Thirty non-carious human premolars were randomly divided into three groups: 1. 0.1% Thymol (T), 2. Distilled water (DW), 3. Dry storage (DS) (control) (n = 10). Dentin moisture was measured with a digital grain moisture meter. Dentin microhardness was measured with the Vickers test. The bond strength was measured with a microshear test. Materials and Methods: Analysis of variance (ANOVA) followed by the Bonferroni test was used for statistical evaluation (p = 0.05). Results: Dentin moisture of the experimental groups was statistically higher than that of the control group (p < 0.05). In addition, the dentin moisture of group DW was significantly higher than that of group T (p < 0.05). The mean microshear bond strength of resin composite to dentin was higher in group DW than in group T and group DS (p < 0.05), while there was no statistical difference between group T and group DS. The microhardness values of all groups were statistically similar. Conclusions: Storage solutions used for disinfection and to prevent dehydration may have negative effects on dentin moisture and bond strength.Öğe EFFECTS OF ERYTHROPOIETIN IN THIOACETAMIDE INDUCED FULMINANT HEPATIC FAILURE IN RATS(Elsevier Science Bv, 2009) Oruc, N.; Ersoz, G.; Yilmaz, F.; Akarea, U. S.; Gunsar, F.; Karasu, Z.; Ozutemiz, O.Öğe EFFICACY AND SAFETY OF RUXOLITINIB IN TURKISH PATIENTS WITH CHRONIC MYELOPROLIFERATIVE NEOPLASMS: A MULTICENTER AND RETROSPECTIVE ANALYSIS(Pergamon-Elsevier Science Ltd, 2017) Soyer, N.; Turgut, M.; Haznedaroglu, I.; Yilmaz, F.; Aydogdu, I.; Pir, A.; Karakus, V.; Ozgur, G.; Kis, C.; Ceran, F.; Ilhan, G.; Ozkan, M.; Arslaner, M.; Ince, I.; Yavasoglu, I.Öğe Evaluation of febrile neutropenic episodes in autologous peripheral blood stem cell transplantation for malignant solid tumors: experience of 30 cases(Nature Publishing Group, 2015) Saydam, G.; Ozkan, M. Comert; Yilmaz, F.; Soyer, N.; Gorcegiz, A. P.; Arda, B.; Uslu, R.; Vural, F.Öğe Expression of Matrix Metal loproteinase Type 9 in Hepatocellular Carcinoma and Correlation with Histopathologic Parameters(Nature Publishing Group, 2009) Nart, D.; Incili, N.; Zeytunlu, M.; Kilic, M.; Karasu, Z.; Yilmaz, F.Öğe Expression of Matrix Metalloproteinase Type 9 in Hepatocellular Carcinoma and Correlation with Histopathologic Parameters(Nature Publishing Group, 2009) Nart, D.; Incili, N.; Zeytunlu, M.; Kilic, M.; Karasu, Z.; Yilmaz, F.Öğe FACTORS CD10, CYTOKERATIN 19 AND STAGING-GRADING SYSTEMS IN PREDICTING THE PROGNOSIS OF PANCREATIC NEUROENDOCRINE TUMORS (PNET)(Editura Acad Romane, 2012) Uguz, A.; Unalp, O. V.; Yeniay, L.; Farajov, R.; Yoldas, T.; Sezer, T. O.; Ipek, N. Y.; Nart, D.; Yilmaz, F.; Sozbilen, M.; Coker, A.Objective. This study was undertaken to examine prognostic factors in patients with pancreatic neuroendocrine tumors (PNET) undergoing surgical treatment to evaluate the prognostic value of recently introduced immunohistochemical staining methods of CD10 and cytokeratin 19. Materials and Methods. Tumors were classified on the basis of 2004 WHO Classification Guidelines and European Neuroendocrine Tumor Society (ENETS) grading system. Immunohistochemical staining with Ki-67, CD10 and cytokeratin 19 was performed. Results. A total of 36 patients with a mean age of 53.7 +/- 12.0 years were included. Overall, 33 patients had a long-term follow-up with 10 patients (30.3%) experiencing recurrence. Seven patients (21.1%) died. Clinical parameters that were associated with recurrence included liver metastasis at the time of surgery and extra-pancreatic invasion (p < 0.005). Positive surgical margins, extra-pancreatic invasion, and multi-focal disease were associated with reduced survival (p < 0.05). In addition, there was an association between survival and WHO 2004 classification (p < 0.05). Conclusions. Although vascular and peripancreatic invasion showed increased risk of recurrence, they were unrelated to survival. Of the histopathological examinations, Ki-67 and mitotic activity showed a correlation with both recurrence and survival, while immunohistochemical staining with cytokeratin 19 and CD 10 did not provide adequate prognostic information.Öğe FIBROSIS SHOULD BE INCLUDED INTO THE NONALCOHOLIC STEATOHEPATITIS SCORING SYSTEM FOR BEING MORE PROGNOSTICATIVE(Elsevier Science Bv, 2009) Gunsar, F.; Yilmaz, F.; Unal, N. G.; Bayrakci, B.; Karasu, Z.; Nart, D.; Ersoz, G.; Akarca, U. S.Öğe THE FREQUENCY AND ASSOCIATION OF KNEE, HIP, HAND AND SPINE OSTEOARTHRITIS IN TURKISH POPULATION: A PRELIMINARY RE PORT OF MULTICENTER LONGITUDINAL STUDY(Springer London Ltd, 2018) Tuncer, T.; Ugur, S.; Nur, H.; Kacar, C.; Akarimak, U.; Altan, L.; Ayhan, F.; Bal, A.; Basaran, S.; Bilgilisoy, M.; Bozbas, G.; Cerrahoglu, L.; Cevik, R.; Coskun, N.; Dagli, Z.; Durmaz, B.; Duruoz, T.; Dulgeroglu, D.; Gurer, G.; Gursoy, S.; Hepguler, S.; Hizmetli, S.; Kaplanoglu, E.; Kaya, T.; Kocabas, H.; Kuran, B.; Melikoglu, M.; Nas, K.; Oncu, J.; Ozcakir, S.; Ozdolap, S.; Saridogan, M.; Sarikaya, S.; Sindel, D.; Sahin, O.; Sendur, O. F.; Tikiz, C.; Ugurlu, H.; Yilmaz, F.Öğe Genetic characterization of grape (Vitis vinifera L.) germplasm from Southeast Anatolia by SSR markers(Jki-Institut Rebenzuchtung, 2011) Boz, Y.; Bakir, M.; Celikkol, B. P.; Kazan, K.; Yilmaz, F.; Cakir, B.; Aslantas, S.; Soylemezoglu, G.; Yasasin, A. S.; Ozer, C.; Celik, H.; Ergul, A.Southeast Anatolia is located in close proximity to the center of origin of grapes and is an important grape producing area of Turkey. The important location of this region for grape genetic diversity together with its diverse ecological conditions may have led to the development of grape germplasm that is unique to this region. However, so far little has been done to genetically analyze this grape germplasm. In this study, we genetically analyzed 55 grape cultivars originating from six different provinces of this region using 14 simple sequence repeat (SSR) loci and a number of ampeolographic characteristics. Based on these analyses, one case of synonymous and four cases of homonymous grape cultivars were identified. The contribution of our results to better characterization of the grape germplasm of the region as well as future germplasm management and breeding efforts is discussed.Öğe GLUTAMINE SYNTHETASE,GLYPICAN-3 AND ARGINSASE-1 EXPRESSION IN THE DIFFERENTIAL DIAGNOSIS OF HEPATOCELLULAR CARCINOMA VS.METASTATIC CARCINOMAS OF THE LIVER(Verduci Publisher, 2019) Argon, A.; Erbil, S.; Nart, D.; Yilmaz, F.Objective: Diagnosis of metastatic liver carcinomas (MLCs) vs. hepatocellular carcinomas (HCCs) may be problematic especially in the non-cirrhotic liver. Glutamine Synthetase (GS), Glypican3 (GPC3, and Arginase-1 (Arg-1) immunohistochemistry can demonstrate the hepatocellular origin of a given tumor. This study aims to investigate the characteristics of GS, GPC3, and Arg -1 expression and the value of their combination in MLCs and in HCCs. Patients and Methods: Tissue samples were obtained from 86 patients with liver tumors, (16 HCCs, 70 MLCs) who underwent liver transplantation or resection. Immunohistochemical staining for GS, GPC3, and Arg-1 was performed on formalin fixed paraffin embedded sections. Demographic, laboratory, and clinical data obtained from patient files were analyzed for the confirmation of the primary origin of the tumors. Statistical analyses were made using the SPSS version 19.0 (IBM, Armonk, NY, USA). Results: Staining pattern of GS and GPC3 was cytoplasmic. Arg-1 staining was cytoplasmic in MLCs vs. cytoplasmic and nuclear in HCCs. Among HCCs, 100%, 38%, and 94% showed positive staining with GS, GPC3, and Arg-1, respectively. Overall, MLCs showed positive staining with GS, GPC3, and Arg-1 in 73%, 4%, and 4% of the cases, respectively. The combination of GS+/GPC3+/Arg-1+ was detectable in 38% of HCCs, but in 0% of MCTs. The specificity of GS, GPC3, and Arg-1 for HCC was 27%, 96%, 96%, and sensitivity was 100%, 38%, and 94%, respectively. Conclusions: Expression of GS in MLCs is high, therefore GS/GPC3/Arg-1 should be used as a panel in addition to other markers when the differential diagnosis of MLC vs HCC is challenging. Cytoplasmic and nuclear Arg-1positivity should be a prerequisite for the diagnosis of HCC.Öğe The incidence and management of acute and chronic rejection after living donor liver transplantation(Elsevier Science Inc, 2006) Yilmaz, F.; Aydin, U.; Nart, D.; Zeytunlu, M.; Karasu, Z.; Kaya, T.; Ozer, I.; Yuce, G.; Aydogdu, S.; Kilic, M.Living donor liver transplantation (LDLT) is a good alternative to cadaveric liver transplantation for end-stage liver disease. Herein we report the outcome of 132 LDLTs performed between 1999 and 2005, with special emphasis on the incidence and management of acute and chronic rejection. Among the LDLT population a first acute rejection episode (ARE) was clinically suspected in 24% and proven by liver biopsy in 11%. According to the Banff classification, 50% of AREs were grade 1, and 50%, grade 2. There was no grade 3 AREs. The first ARE occurred between 7 days and 23 months posttransplantation (mean 97 days, median 70 days). Ninety-seven percent (31/32) of the AREs occurred within the first year after transplantation and 3% (1/32) in the second year. Among the patients with ARE, 23% developed a second ARE between 4 and 11 months. A third ARE was detected in 8% of patients after month 18. All AREs responded to adjustment of immunosuppressive doses or steroid boluses. Chronic rejection (CR) was detected in 2%. In conclusion, the incidences of ARE and CR are consistent with the previously reported data. Acute and chronic rejections seem to be mild and easily manageable clinical conditions. Our results also showed a significant difference between clinically suspected and biopsy-proven ARE emphasizing the importance of indicated liver biopsies in the management of the LDLT population.Öğe Intraductal papillary neoplasm of the bile duct: clinicopathological characteristics and insulin-like growth factor II mRNA binding protein 3 (IMP3) expression in 24 cases(Springer, 2019) Buyuktalanci, E.; Damirli, A.; Tekin, F.; Uguz, A.; Unalp, V.; Zeytunlu, M.; Nart, D.; Ersoz, G.; Ozutemiz, O.; Yilmaz, F.Öğe Intrahepatic Cholangiocarcinoma Arising in Chronic Viral Hepatitis-Associated Cirrhosis: Two Transplant Cases(Elsevier Science Inc, 2008) Nart, D.; Ertan, Y.; Pala, E. E.; Zeytunlu, M.; Kilic, M.; Yilmaz, F.Hepatitis C vir-us (HCV) or hepatitis B virus (HBV)-related cirrhosis is known to be a risk factor for hepatocellular carcinoma (HCC). Recently, these viruses have been reported to have an etiologic role in the development of intrahepatic cholangiocarcinoma (ICC). Herein we have reported two cases of HCV- and HBV-related cirrhosis with ICC in whom the pretransplant diagnosis was HCC. The patient with HCV cirrhosis, was a 47-year-old woman with a large nodule in the right lobe. The patient with HBV cirrhosis was a 45-year-old man with two nodules. Serum tumor marker levels, carcinoembryonic antigen (CEA), alphafetoprotein (AFP), and carbohydrate antigen 19-9 (CA 19-9) were determined before live donor liver transplantation (LDLT). The patient with HCV cirrhosis showed mildly elevated serum levels of AFP. The patient with HBV cirrhosis showed an elevated CA 19-9 level. On microscopic examination, all nodules exhibited typical morphological findings of adenocarcinoma. The patient with HCV cirrhosis developed brain metastases 4 years after LDLT. The patient with HBV cirrhosis is disease-free at 18 months after transplantation. In cirrhotic patients with active malignancy who are candidates for LDLT, ICC should be considered in the differential diagnosis. Although the literature is limited, selected patients with ICC may benefit from LDLT.Öğe Isolated hepatic sarcoidosis mimicking liver microabscesses: a case report(Springer London Ltd, 2014) Tasbakan, M. I.; Erdem, H. A.; Pullukcu, H.; Yamazhan, T.; Sipahi, O. R.; Tasbakan, M. S.; Ceylan, N.; Yilmaz, F.; Arda, B.; Ulusoy, S.Öğe Ki-67 scoring in neuroendocrine tumors of the pancreas: Alternative solutions(Springer, 2013) Cinar, E.; Aykutlu, U.; Basar, E.; Uguz, A.; Uluer, H.; Ipek, F. N.; Coker, A.; Yilmaz, F.Öğe Lamivudine monoprophylaxis prevents HBV infection in recipients undergoing live donor liver transplantation because of non-HBV related diseases, having their grafts from core-antibody positive donors(Elsevier Science Bv, 2007) Karasu, Z.; Akyildiz, M.; Ozacar, T.; Yilmaz, F.; Akarca, U. S.; Ersoz, G.; Gunsar, F.; Aydin, U.; Kilic, M.; Ilter, T.