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Öğe "Air-bubble" signs in the CT diagnosis of perforated pulmonary hydatid cyst: Three case reports(2008) Zeyrek D.; Savas R.; Gulen F.; Demir E.; Tanac R.Computed tomography is an important imaging modality in the evaluation of hydatid cyst. However, diagnosis of perforated hydatid cyst is very difficult and for this reason some radiological findings have been defined. An important finding is the "air bubble" sign. As a consequence of cyst rupture, secondary bacterial infections like bronchopneumonia or lung abscess may develop which complicate the clinical picture further. In the literature, the "air bubble" sign which is a relatively newly discovered radiological sign is reported to be very sensitive in establishing diagnosis. For this reason, in suspected cases of hydatid cyst, the air bubble sign may aid physicians in establishing diagnosis.Öğe Association of interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in Turkish children with atopic asthma(2008) Zeyrek D.; Demir E.; Alpman A.; Özkınay F.; Gulen F.; Tanac R.Asthma is a complex genetic disease. Genetic and functional characteristics of interleukin (IL)-1 support a role as an asthma locus for the IL-1 family on chromosome 2q12-21. This study was performed to investigate the relationship between polymorphisms of IL-1beta promoter region -511C/T and IL-1 receptor antagonist (IL-1Ra) gene (IL-RN) and bronchial asthma in Turkish children. Children were divided into two groups: (1) bronchial asthma (n = 328) and (2) healthy control (n = 246). Polymerase chain reaction was used to resolve the IL-1beta -511C/T and the IL-1Ra intron 2 polymorphisms. Plasma IgE concentrations were measured by immunoassays, and skin-prick tests were done in children with atopic diseases. The number of genotype CC and C allele in the control groups in IL-1beta -511C/T polymorphisms increased. The number of genotype 1/1 in the asthma groups and genotypes 1/2 and 5/5 and 5 allele in the control groups in IL-1Ra intron 2 gene polymorphism increased. Serum spIgE level increased in the 2/2 genotype in the asthma groups in IL-1Ra intron 2 gene polymorphism. Based on these results, we conclude that there was an association of pediatric asthma with the IL-1beta -511C/T and IL-1Ra intron 2 gene polymorphism. Based on these findings, it has been proposed that IL-1beta -511C/T and IL-Ra intron 2 gene polymorphism are useful markers for prediction of asthma. Copyright © 2008, OceanSide Publications, Inc., U.S.A.Öğe Clinical and hemodynamic features of Eisenmenger syndrome patients at the time of first admission: A tertiary referral-center experience [Eisenmenger sendromlu hastalari{dotless}n ilk başvuru ani{dotless}ndaki klinik ve hemodinamik özellikleri: Tersiyer merkez deneyimi](2012) Güngör H.; Ertugay S.; Ayik M.F.; Demir E.; Engin Ç.; Yagdi T.; Özbaran M.; Atay Y.; Nalbantgil S.Objective: In this study, patients admitted with the diagnosis of Eisenmenger syndrome (ES) in a tertiary referral center were analyzed. Methods: The data of 20 consecutive patients (mean age: 27.6+1.8 years, 7 male and mean follow-up time: 35.6±9.1 months) with ES were retrospectively analyzed. Demographic characteristics, symptoms, physical examination, laboratory and hemodynamic parameters were analyzed at the time of first admission. Results: The most frequent underlying heart diseases were ventricular septal defect (VSD) with complex congenital disease (n:8, 40%) and isolated VSD (n:7, 35%). 6-minute walking test distance was 347.9±33.7 meters and 15 patients (75%) had a functional capacity of NYHA Class III, at the time of admission. ES was diagnosed with catheterization in all patients and mean systolic pulmonary arterial pressure measured by catheterization was 112±6.8 mmHg. Pulmonary function tests, FVC (forced vital capacity), FEV 1 (forced expiratory volume), FEV 1/FVC values were respectively, 3.1±0.4, 2.5±0.4 L and 76.7±3.3%. Metabolic tests were performed in all patients at the first visit. Mean VO2 max was 16.7 ±1.0 ml / kg/min and VE/VCO2 rate was 53.9±3.2%. Although PH and partial pressure of carbon dioxide levels were within normal range in blood gas analysis, oxygen saturation and partial pressure of oxygen levels were low. Conclusion: The most common underlying heart disease of ES patients is VSD. In this cases exercise capacity is restricted and this restriction is reflected in laboratory parameters. © 2012 by AVES Yayi{dotless}nci{dotless}li{dotless}k Ltd.ss}k Ltd.Öğe Comparison of Clinical Presentations and Disease Severity of Children Hospitalized with Influenza A and B(AVES, 2024) Eşki A.; Öztürk G.K.; Çiçek C.; Gülen F.; Demir E.Objective: This study compared the clinical presentations and disease severity between influenza A and B (FLUA and FLUB). Materials and Methods: The study included children hospitalized with virologically confirmed influenza between 2010 and 2020. The severity of the disease was evaluated based on admission to the pediatric intensive care unit (PICU), mechanical ventilation requirement, length of hospital stay, length of stay in the PICU, and death. Influenza viruses were compared within predefined age groups (0-2, 3-9, and 10-18 years) and in all age groups. Results: Of 343 patients, FLUA and FLUB were detected in 75.8% and 24.2% of children, respec-tively. FLUB was associated with a higher incidence of headache and abdominal pain (P <.001 and P =.01). Children with FLUB were prescribed antibiotics and antivirals 0.56 and 0.58-fold fewer than those with FLUA. Headache and abdominal pain rates were higher in patients between 3 and 9 years with FLUB. Children between 0 and 2 years with FLUA were more fre-quently admitted to the PICU than those with FLUB (23.6% vs. 4.0%; P <.004). Eight patients with FLUA died, while only 1 with FLUB died (P =.69). Conclusion: The clinical presentation of FLUA and FLUB appeared similar, except for headache and abdominal pain, which were more prevalent in older patients with FLUB. Our study revealed that children between 0 and 2 years with FLUA were at a significantly higher risk for admission to the PICU. As a result, greater attention and awareness should be paid to children under 2 years old with FLUA. © 2024, AVES. All rights reserved.Öğe Cut-Off Values of Specific IgE and Skin Prick Test to Predict Oral Food Challenge Positivity in Children with Cow’s Milk Allergy(AVES, 2022) Günaydın N.C.; Akarcan S.E.; Gülen F.; Bal C.M.; Tanaç R.; Atasever M.; Demir E.Objective: The cut-off values for the skin prick test diameters and cow’s milk-specific IgE mea-surements are used to predict the result of the oral food challenge test for the diagnosis of cow’s milk allergy. This study aimed to determine the diagnostic values of skin prick test and cow’s milk-specific IgE according to age groups and compare the diagnostic powers of these 2 methods. Materials and Methods: In total, 153 children who had a preliminary diagnosis of cow’s milk allergy were evaluated. Group A (n = 90) consisted of cow’s milk allergy patients whose diagnosis was confirmed by a positive oral food challenge or a history of anaphylaxis. Group B (n = 63) was composed of patients with a negative oral food challenge. The demographic, clinical, and laboratory findings of 2 groups were compared. Results: The cut-off points for cow’s milk-specific IgE and cow’s milk-skin prick test were determined as >2.12 kUA/L and >5 mm, respectively. The area under the curve was 0.844 for cow’s milk-skin prick test (sensitivity 73%, specificity 84%) and 0.745 for cow’s milk-specific IgE (sensitivity 67%, specificity 86%). The diagnostic power of skin prick test was determined to be higher when compared to cow’s milk-specific IgE (P = .02). According to the predicted probability curves, decision points for cow’s milk-specific IgE and cow’s milk-skin prick test with 95% probability were determined as follows, respectively: for ?24 months: 22 kUA/L, 11.3 mm; for >24 months: 44.1 kUA/, 15.1 mm. The lowest cut-off value with a positive predictive value of 95% and a specificity of 96% was found in patients <1-year-old (>3.3 kUA/L) Conclusion: The use of high probability diagnostic values of communities for specific IgE anskin prick test along with a significant clinical history may provide accurate and rapid diagnosof cow’s milk allergy and facilitate patient follow-up. © 2022, AVES. All rights reserved.Öğe Effect of inhaled steroid therapy on distribution of Tc-99m DTPA radioaerosol in asthmatic children.(2000) Yüksel H.; Yüksel D.; Demir E.; Tanaç R.; Kayaliodlu M.The aim of this study was to evaluate the effect of inhaled steroid therapy on the distribution of inhaled Tc-99m DTPA in asthmatic children. Twenty-one asthmatic children and 15 healthy controls were entered in this study. The distribution of radioaerosols was scored by using a modified standardized score system over both lungs and expressed as homogeneity score/patient. The baseline homogeneity score was calculated before the inhalation therapy of budesonide (400 micrograms/day) for six months. The homogeneity score was repeated at the end of the second and sixth months of therapy. Asthmatic symptom scores and peak-flow rate variability, which were observed to improve throughout the study, were also recorded. Although homogeneity scores of the controls demonstrated no abnormality, mean baseline homogeneity scores of asthmatics was significantly high, 1.7 +/- 0.4/patient, and decreased to 0.6 +/- 0.2 and 0.3 +/- 0.1/patient at the end of second and sixth months, respectively (p < 0.05). These results revealed significant improvement in the radioaerosol distribution after inhaled steroid therapy. It was concluded that the lack of homogeneity in the distribution of Tc99m-DTPA in the lung, as an indicator for ventilation defects, may be accepted as a useful, noninvasive tool to monitor the efficacy of the therapy with inhaled agents in childhood asthma.Öğe Effect of nedocromil sodium on invivo and invitro secretion of lipid mediators from peripheral leukocytes of asthmatic children(1997) Huseyinov A.; Yuksel H.; Tanac R.; Demir E.; Coker I.[No abstract available]Öğe Eponym: Scimitar syndrome(Springer Verlag, 2010) Midyat L.; Demir E.; Aşkın M.; Gülen F.; Ülger Z.; Tanaç R.; Bayraktaroğlu S.Scimitar syndrome is a rare congenital anomaly, characterized by partial or complete anomalous pulmonary venous drainage of the right or left lung into the inferior vena cava. The syndrome is commonly associated with hypoplasia of the right lung, pulmonary sequestration, persisting left superior vena cava, and dextroposition of the heart. The pathogenesis of the syndrome is unclear, but it seems to originate from a basic developmental disorder of the entire lung bud early in embryogenesis. Two main forms of scimitar syndrome have been described. Signs and symptoms can start during infancy (infantile form) or beyond (childhood/adult form). The infantile form generally presents within the first 2 months of life with tachypnea, recurrent pneumonia, failure to thrive, and signs of heart failure. The diagnosis of scimitar syndrome is usually made based on the characteristic chest X-ray films and can be confirmed by angiography; however, it is now done mostly by transthoracic or transesophageal echocardiography, noninvasive computed tomography, or magnetic resonance angiography. Fetal echocardiography using three-dimensional power Doppler imaging permits prenatal diagnosis. Most frequently, patients are asymptomatic in the absence of associated abnormalities and can be followed conservatively. For patients with congestive heart failure, repeated pneumonia, or pulmonary-to-systemic blood flow ratios greater than 1.5 and pulmonary hypertension, it is important to reroute the anomalous right pulmonary veins and repair the associated cardiac defects in order to avoid progression to right ventricular failure. The triad of respiratory distress, right lung hypoplasia, and dextroposition of the heart should alert the clinician to think of scimitar syndrome. © 2010 Springer-Verlag.Öğe The evaluation of late sequelae of tetanus infection(Springer India, 1994) Tutuncuoglu S.; Demir E.; Koprubasi F.; Selcuki D.Tetanus is still an important cause of morbidity and mortality in developing countries. Fifty two patients with tetanus were admitted within a 15 year period to our hospital, and 24 of them died. The remaining cases were called for re-evaluation 3-13 years after the infection. Only 10 cases were admitted again, and 6 of them recovered from neonatal tetanus. Their neurological examinations were unremarkable with 5 of them having mild mental retardation. Their EEG's were normal except for one case who had epileptic focus. Their visual and brainstem evoked potentials (VEP, BAEP) were measured and they were in normal ranges. Their results were compared with the results of a control group which consisted of 9 healthy children of matched age and sex. © 1994 Dr. K C Chaudhuri Foundation.Öğe Examination of factors affecting health school student's health promotion behavior [Saglik yüksekokulu ögrenci·leri·ni·n sagligi geli·şti·rme davranişlarini etki·leyen etmenleri·n i·ncelenmesi·](2009) Oyur Çelik G.; Malak A.T.; Bektaş M.; Yilmaz D.; Sami Yümer A.; Öztürk Z.; Demir E.This semi-experimental study was conducted at examining of factors affecting health school student's health promotion behaviour. The study sample consist of 156 first and second grade students Çanakkale Onsekiz Mart University School of Health. The data were collected by socio-demographic data collection form and Healthy Lifestyles Behavior Scale (HLBS) between October and December 2008. The data were analyzed using percentage, independent t-test, Paired sample t-test, kruskal wallis and bonferroni adjusted mann-whitney U statistical methods. The researcher gave education the student who participate the study about self-breast examination, testicular examination, gynecologic cancer prevention, nutrition, smoking, the importance of exercise. The average age of students participating in the study 19.4 + 1.3, 67.9 % of women and 32.1% of the male. 40.4 % of the students' live in the city, 79.5 % of the nuclear family and 51.9 % in order to graduate high school. Healthy lifestyle behaviors scale pre-education scores average was 122.1 ± 19.8. No significant difference was found between HLBS scores according to gender, graduate school, department, family type and family's economic level. After three months of education, student's HLBS score was 125.3 ± 17.4. There was a significant difference between the pre- post education HLBS scores (p <0.05). After three months of education, the average HLBS score of the students at the middle level were found. Students are required to improve positive health behaviors.Öğe The Fc?RIIa polymorphism in Turkish children with asthma bronchial and allergic rhinitis(2007) Gulen F.; Tanac R.; Altinoz S.; Berdeli A.; Zeyrek D.; Koksoy H.; Demir E.Objective: The aim of the present study was to evaluate the Fc?RIIa polymorphism in Turkish children with atopic asthma and allergic rhinitis. Design and methods: In this study, 372 atopic children (192 asthma bronchial, 180 allergic rhinitis) between ages of 5 and 16 years old (11.3 ± 2.9) who were followed at Aegean University Paediatric Allergy and Pulmonology Outpatient Clinics and 234 healthy subjects as the control group were included. The evaluation of subjects included routine biochemical blood analysis and allergic workup based on the following laboratory determinants. The Fc?RIIa polymorphism was determined using the polymerase chain reaction method. Results: Distribution of R131R genotype was significantly different among patient groups compared to controls (for asthmatic children OR: 2.64 95%CI: 1.22-5.79, p = 0.006; for allergic rhinitis OR: 2.58 95%CI: 1.18-5.71, p = 0.009). Frequency of 131R allele was significantly different among patient groups compared to controls (for asthmatic children OR: 1.66 95%CI: 1.22-2.26, p = 0.0007; for allergic rhinitis OR: 1.93 95%CI: 1.42-2.63, p = 0.00001). Conclusion: This study shows that Fc?RIIa gene 131R allele represents an important genetic risk factor for bronchial asthma and allergic rhinitis susceptibility. © 2007 The Canadian Society of Clinical Chemists.Öğe Fc?RIIIa-V/F 158 polymorphism in Turkish children with asthma bronchiale and allergic rhinitis(2008) Zeyrek D.; Tanac R.; Altinoz S.; Berdeli A.; Gulen F.; Koksoy H.; Demir E.Fc receptors (FcR) play an important role in immune regulation. This might be linked to the variability in immune response, therefore relating to the pathogenesis of atopic diseases. The aim of the present study was to evaluate the Fc?RIIIa gene polymorphism in Turkish children with asthma and allergic rhinitis. The study included 364 atopic children (184 bronchial asthma, 180 allergic rhinitis) and 234 healthy subjects as the control group, aged between 5 to 16 years. Patients were recruited from outpatient clinics of allergy and general pediatric care. Plasma IgE concentrations were measured by immunoassays and skin prick test was done in children with atopic diseases. The Fc?RIIIa gene polymorphism was determined using the polymerase chain reaction method. Distribution of V158V genotype was significantly different among patient groups compared to controls (for asthmatic children OR: 5.33, 95% CI: 2.80-10.23, p < 0.001; for allergic rhinitis OR: 3.25, 95% CI: 1.75-6.07, p = 0.001). Distribution of 158 V allele was significantly different among asthmatic children (OR: 2.20, 95% CI: 1.65-2.92, p < 0.001) and allergic rhinitis patients (OR: 1.77, 95% CI: 1.32-2.35, p < 0.001) compared to healthy controls. Our study shows that the V158V genotype in Fc?RIIIa gene polymorphism may be a genetic risk factor for the development of atopic diseases. © 2008 The Authors.Öğe Immediate Adverse Reactions to Immunotherapy(2003) Can D.; Demir E.; Tanaç R.; Gülen F.; Yenigün A.Background: Immunotherapy, which has been used since the beginning of this century, has potential adverse reactions. The purpose of this study was to evaluate immediate local and systemic reactions to allergen immunotherapy and to compare rates of adverse reactions to aluminum-adsorbed versus calcium-adsorbed allergen vaccines. Methods: 108 cases (38 girls and 70 boys) were given allergen immunotherapy between 1997 and 2001. The following data were recorded for each patient: primary disease being treated (allergic rhinitis, asthma, or allergic rhinitis and asthma), allergic sensitivities (dust mite or grass pollen), number of injections, the stage of immunotherapy (buildup or maintenance), dilution of allergen vaccine, and type of allergen vaccine (calcium- or aluminum-adsorbed). Adverse reactions were classified as systemic or local. Local reactions were classified as hyperemia and induration less than 5 cm, more than 5 cm, itching, and pain. Results: 4783 injections were evaluated in 108 subjects: with allergic rhinitis (44%), asthma (40%), allergic asthma, and rhinitis (16%). Frequency of immediate systemic reaction was 0.13%. Frequency of immediate local reactions were: hyperemia and induration less than 5 cm 3%, greater than 5 cm 0.16%, local-itching 0.15%, and local pain 0.2%. There was no significant difference in systemic and local reactions between calcium- and aluminum-adsorbed vaccines. Immediate local reactions were more frequent during maintenance therapy compared to buildup. Subjects were-more likely to have local reactions during maintenance therapy if they had allergic rhinitis (p < 0.05) of were receiving grass pollen vaccine (p < 0.01). Conclusion: Immediate adverse reactions were uncommon when given to children with asthma and allergic rhinitis. Aluminium- and calcium-adsorbed allergen vaccines showed similar rates of systemic and local reactions.Öğe Immediate adverse reactions to subcutaneous allergen specific immunotherapy in respiratory allergies(2010) Midyat L.; Demir E.; Gülen F.; Karadeniz C.; Can D.; Tanaç R.Objective: Allergen immunotherapy has been used in the management of allergic diseases for nearly a hundred years; however, its short term side-effects can effect the decision of starting the therapy. Material and Methods: This study is a retrospective evaluation of the immediate local and systemic reactions seen in the cases who were given immunotherapy between March 1997 and September 2008 in the Ege University Faculty of Medicine, Department of Pediatric Allergy and Pulmonology. Results: The 541 patients had ages ranging from 6 to 18 years. 64.3% (n=348) of the patients were having calcium phosphate-adsorbed allergen vaccines, while35.7% (n=193)were having aluminium hydroxide adsorbed vaccines. Of the patients, 229 patients had allergic rhinitis (42.3%), 161 had asthma (29.7%), and 151 had both asthma and allergic rhinitis(27.9%). Totally, 28.374 injections were given to the patients. In 4.6% (n=1310) of the injections immediate reactions were detected; 74% (n=970) of them were observed during the build-up therapy (p<0.01), and 81.6% (n=1069) of the reactions were detected in the patients who were receiving calcium phosphate-adsorbed vaccines (p< 0.01). There was no statistically significant difference in the immediate reaction rates of the subjects when comparing the allergens in the vaccines or the diagnosis of the patients. The frequency of systemic reactions was 0.04% (n 13); most of these reactions were detected during the build-up therapy and in patients with asthma + allergic rhinitis. With early term interventions, the symptoms of all patients improved in a short time. Conclusion: In conclusion, most of the immediate reactions to immunotherapy are local and the systemic ones are controllable through early treatment; so that subcutaneous immunotherapy is a safe treatment modality when it is used for appropriate indications by experienced staff. Copyright © 2010 by Türkiye Klinikleri.Öğe MicroRNA expression profiling in children with different asthma phenotypes(John Wiley and Sons Inc., 2016) Midyat L.; Gulen F.; Karaca E.; Özkınay F.; Tanac R.; Demir E.; Cogulu O.; Aslan A.; Özkınay, Cihangir; Onay H.; Atasever M.An improved understanding of the molecular mechanisms in asthma through exploring the role of microRNAs may offer promise to reveal new approaches for primary prevention and identification of new therapeutic targets in childhood asthma. The primary goal of this study is to identify the microRNAs that play a role in the pathogenesis of asthma in pediatric age group. The secondary goal is to analyze these microRNAs according to the asthma phenotype, atopic status, and severity of the disease exacerbation. To our knowledge, this is the first research project in the literature which studies the relationship between microRNA expression and the severity of childhood asthma. One hundred children between 6 and 18 years old with a diagnosis of asthma, and 100 age-matched healthy children were enrolled in this study, and the analyses of microRNA expression profiles were performed in the Medical Genetics Laboratories of Ege University between November 2009 and June 2010. The expression of 10 microRNAs were shown to be higher in patients with more severe asthma, and the expression of these microRNAs were also found to be higher in patients who present with more severe acute asthma exacerbation symptoms (P<0.001). Also, five microRNAs were found to be expressed more than twofold in allergic patients when compared to non-allergic participants (P<0.001). Asthma is one of the best examples of complex genetic diseases, and further studies, which will investigate the relationship between these microRNA’s and their target genes, are needed to learn more about the specific roles of microRNAs in respiratory diseases. Pediatr Pulmonol. © 2015 Wiley Periodicals, Inc.Öğe One case, two "firsts": First successful double lung and first pediatric lung transplantation in Turkey [Bir olgu, iki ilk: Türkiye'de ilk başarili çift akciger transplantasyonu; pediatrik yaş grubunda Türkiye'de ilk akciger transplantasyonu](2010) Özbaran M.; Turhan K.; Yagdi T.; Gülen F.; Özcan C.; Engin Ç.; Midyat L.; Çagirici U.; Nart D.; Nalbantgil S.; Demir E.; Tanaç R.; Aşkar F.We report the first successful double-lung transplantation in all age groups as well as the first lung transplantation in the pediatric age group in our country. A 14-year-old male who was oxygen dependent for the last three years was diagnosed with septic lung disease and bronchiolitis obliterans. He was followed-up by the "heart and lung transplantation group" of our hospital for approximately one year under non-invasive mechanical ventilatory support while on the lung transplantation waiting list. A sequential double lung transplantation was performed on April 08, 2009. He is now on his 11th month postoperatively and is healthy.Öğe Pemphigus vulgaris in childhood. A case report(2008) Koturoglu G.; Demir E.; Kumbaraci B.S.; Kandiloglu G.; Yurtsever S.N.An 11-year-old girl with vesicles and eroded lesions on her oral mucosa and tongue was diagnosed as having pemphigus vulgaris. The diagnosis was confirmed by histopathologic and immunofluorescence studies. The patient was succesfully treated with methylprednisolone and azathioprine. After two months maintenance therapy was started. She is still taking methylprednisolone and azathioprine as maintenance therapy and no recurrence has been observed.Öğe Plasma interleukin-3 and interleukin-4 concentrations in Turkish asthmatic children [2](BMJ Publishing Group, 1995) Kutukculer N.; Ozdogru E.; Demir E.; Tanac R.[No abstract available]Öğe The psychiatric follow-up process of a lung transplantation case [Bir akciger nakli olgusunda psikiyatrik izlem süreci](2010) Özbaran B.; Erermiş S.; Gülen F.; Midyat L.; Turhan K.; Demir E.; Yagdi T.; Tanaç R.; Özcan C.; Engin Ç.; Özbaran M.Organ transplantation practices are increasing worldwide and in our country and patient care opportunities are improving. Organ transplantation process generally includes transplant preparation, coping with disease, transplantation operation and post-transplantation period. Psychiatrists take part in the transplantation team and support the team and the patient, offer treatment if necessary. In this report the psychiatric symptoms and treatment of the first living pediatric case after double lung transplantation were reported. The fifteen years old, male case was followed since age of fourteen in Ege University Medical School Pediatrics Clinic, Respiratory System and Allergy Department with diagnoses of bronchiolitis obliterans, bronchiectasis and pulmonary hypertension and indicated double lung transplantation in year of 2008. In April 2009, the first double lung transplantation surgery in Turkey in pediatric age group was done. In 15th day after transplantation anxiety symptoms were occurred and these symptoms were limited and disappeared with brief supportive interventions. In fifth month after transplantation depressive symptoms were occurred and the case was diagnosed as depressive disorder and treated with fluoxetin 20 mg/day. Psychosocial interventions were also undertaken for his edu-education. The case is still in follow-up in Ege University Child Psychiatry Clinic, Consultation Liaison Department.Öğe Pulmonary manifestations of chronic liver disease(1999) Avdoğdu S.; Gökşen D.; Özyürek S.; Demir E.; Dorak C.; Selimoğlu M.A.; Parlar A.; Tanaç R.; Yağci R.V.[No abstract available]