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Öğe The impact of a videoconferencing-ımplemented program on older adults' psychosocial health in the COVID-19 pandemic: an experimental study(John Wiley and Sons Inc, 2023) Yavuz, C.; Şahin, S.Background: Social distancing and ‘stay-at-home’ orders are essential to contain the coronavirus outbreak; however, it has affected older adults very negatively psychosocially. The present study explored the impact of a videoconferencing-implemented program on older adults' psychosocial health during the COVID-19 pandemic. Methods: We carried out this experimental research with pretest-posttest and control groups between November 02 to December 26, 2020 on individuals aged 60 years and over who were enrolled at Fethiye Refreshment University (60+ FRU). While the intervention group consisted of 40 people, we recruited 52 participants in the control group. Unlike the control group, the intervention group participated in a structured videoconferencing program held there days a week for 8 weeks. We collected the data using the Fear of COVID-19 Scale (FCV-19S), the Multidimensional Scale of Perceived Social Support (MSPS), the Depression Anxiety Stress Scale (DASS-21), and the Loneliness Scale for Elderly (LSE). The data were then analysed on the SPSS 22.0 program. Results: The participants had a mean age of 66.13 ± 5.13 years; 65.2% were females, 58.7% were married, 55.4% held a university degree and 93.5% had a regular income. Following the intervention, we found the experimental group to have significantly a lower posttest FCV-19S score (p < 0.05) and a higher posttest MSPS score than the control group (p < 0.05). Besides, the experimental group had significantly lower posttest scores on the DASS-21 and the anxiety and stress subscales than the control group (p < 0.05). Moreover, the posttest score of the experiential group on the emotional loneliness subscale (LSE) was found to be significantly lower than that of the control group (p < 0.05); nevertheless, we could not conclude significant differences between the groups’ pretest and posttest LSE scores and their scores on the other LSE subscales (p > 0.05). Conclusion: Overall, the videoconferencing program was found to be efficient in providing older adults with psychosocial support amid social isolation. © 2023 Japanese Psychogeriatric Society.Öğe Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study(Elsevier Masson s.r.l., 2023) Kısaarslan, A.P.; Çiçek, S.Ö.; Batu, E.D.; Şahin, S.; Gürgöze, M.K.; Çetinkaya, S.B.; Ekinci, M.K.Introduction: Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE). Aim: To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population. Methods: This study was based upon 24 referral centers’ SLE cohorts, multicenter and multidisciplinary network in Turkey. Patient data were collected by a case report form which was standardized for NP definitions according to American Collage of Rheumatology (ACR). Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) neuropsychiatric part was used to determine NP damage. Variables were evaluated Ward's hierarchical clustering analyses, univariate, and multivariate logistic regression analyses. Results: A hundred forty-nine of 1107 jSLE patients had NP involvement (13.5%). The most common NPSLE findings were headache (50.3%), seizure (38.3%), and acute confusional state (33.6%). Five clusters were identified with all clinical and laboratory findings. The first two clusters involved neuropathies, demyelinating diseases, aseptic meningitis, and movement disorder. Cluster 3 involved headache, activity markers and other SLE involvements. Idiopathic intracranial hypertension, cerebrovascular disease, cognitive dysfunction, psychiatric disorders and SLE antibodies were in the fourth, and acute confusional state was in the fifth cluster. In multivariate analysis, APA positivity; OR: 2.820, (%95CI: 1.002–7.939), P: 0,050, plasmapheresis; OR: 13.804 (%95CI: 2.785–68.432), P: 0,001, SLEDAI scores; OR: 1.115 (%95CI: (1.049–1.186), P: 0,001 were associated with increased risk for neurologic sequelae. Conclusion: We detected the prevalence of juvenile NPSLE manifestations in Turkey. We have identified five clusters that may shed light pathogenesis, treatment and prognosis of NP involvements. We also determined risk factors of neurological sequelae. Our study showed that new definitions NP involvements and sequelae for childhood period are needed. © 2023 Société française de rhumatologieÖğe Physiology of ageing(Wiley, 2022) Şahin, S.; Taşkıran, E.Theories of ageing can be classified as error theories (stochastic theories) and programmed theories. This chapter discusses changes in organs and systems that occur due to the pathogenetic mechanisms identified in the theories of ageing. The systems covered include nervous system, cardiovascular system, endocrine system, gastrointestinal system, immune system, musculoskeletal system, and respiratory system. In previous decades, the ageing process was thought to be correlated with a decline in hormonal function throughout life. Studies were conducted involving the transplantation of animal endocrine glandular extracts into humans. Age-related changes in the urinary tract are mostly inevitable. Decreasing renal function is a challenging factor for the appropriate dosing of medications in the setting of multiple comorbidities. Physiologic changes in the urinary tract are discussed. The skin dermis loses its thickness with age. © 2022 John Wiley & Sons Ltd. All rights reserved.Öğe Relationship Between Polypharmacy and Geriatric Syndromes in Older Nursing Home Residents(Galenos Publishing House, 2022) Koçak, F.Ö.K.; Taşkıran, E.; Şahin, S.Objective: Our aim is to determine the prevalence of polypharmacy and the relationship between polypharmacy and geriatric syndromes as well as comorbidity in older nursing home residents (NHR). Materials and Methods: This observational and cross-sectional study was conducted with 217 adults ?60 years of age who had Katz index of Independence in activities of daily living score over 4 points and were institutionalized at nursing care home from March to April 2019. Polypharmacy was defined as the daily use of 5 or more medications. Geriatric syndromes include dementia, depression, urinary incontinence (UI), malnutrition, falls, mobility problems, hearing loss, vision impairment. Results: The prevalence of polypharmacy among NHR was 61.8%. By univariate analysis, polypharmacy was associated with chronic diseases such as heart disease, chronic obstructive pulmonary disease (COPD) and diabetes mellitus, and with geriatric syndromes such as dementia, depression, UI, and mobility problems (p<0.05). In the multivariate analyses, depression [odds ratio (OR) =9.57; 95% confidence interval (CI), 2.73-33.60] and mobility problems (OR= 4.88; 95% CI, 1.80-13.25) increased polypharmacy by 9.6 and 4.9-fold respectively. Conclusion: Comorbidity and geriatric syndromes play an important role in the development of polypharmacy. Monitoring polypharmacy is often necessary as well as giving complex medication regimens for NHR. © Copyright 2022 by the Academic Geriatrics Society / European Journal of Geriatrics and Gerontology published by Galenos Publishing House.